Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569467 | 0.87 | TSHR (0.51) | TDP1POLBAPEX1HTTSMN1; SMN2 | |
| SCHEMBL7951993 | 0.82 | MAPT (0.42) | TDP1POLBAPEX1HTTSMN1; SMN2 | |
| SCHEMBL235139 | 0.79 | MTNR1A (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8415435 | 0.78 | THRB (0.45) | TDP1POLBAPEX1HTTSMN1; SMN2 | |
| SCHEMBL305728 | 0.76 | POLB (0.44) | TDP1POLBAPEX1HTTSMN1; SMN2 | |
| SCHEMBL31740246 | 0.75 | ALDH1A1 (0.43) | TDP1POLBAPEX1HTTSMN1; SMN2 | |
| SCHEMBL4455176 | 0.75 | TDP1 (0.42) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL13801021 | 0.75 | HPGD (0.44) | TDP1POLBAPEX1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11047494 | 0.75 | POLB (0.43) | TDP1POLBAPEX1HTTSMN1; SMN2 | |
| SCHEMBL1087332 | 0.75 | NPC1 (0.60) | TDP1SMN1; SMN2TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150094448-A1 | SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES | MEDIPACS, INC. | 2015-04-02 | — | — | US | disclosed |