Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725552 | 0.89 | ALDH1A1 (0.52) | ALDH1A1NPSR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL9725384 | 0.84 | ALDH1A1 (0.56) | ALDH1A1NPSR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL5341171 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL22478744 | 0.78 | ALDH1A1 (0.50) | ALDH1A1NPSR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL8985656 | 0.77 | KAT2B (0.64) | ALDH1A1NPSR1SMN1; SMN2MAPTBCHE | |
| Hydrochloric Acid SCHEMBL9760520 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1NPSR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL5343044 | 0.76 | MAPT (0.55) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL17678162 | 0.76 | ALDH1A1 (0.59) | ALDH1A1NPSR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL5352344 | 0.76 | ALDH1A1 (0.80) | ALDH1A1NPSR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7745736 | 0.76 | ALDH1A1 (0.59) | ALDH1A1NPSR1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | disclosed |
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | disclosed |
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | disclosed |
| US-7238813-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238813-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238813-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-20040082583-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249600-A1 | CHEMICAL COMPOUNDS | TIE1, KDR, FLT4 | ALDH1A1 955/4885NPSR1 4582/4885SMN1; SMN2 4300/4885 |
| US-20040082583-A1 | Chemical compounds | TIE1, KDR, FLT4 | ALDH1A1 955/4885NPSR1 4582/4885SMN1; SMN2 4300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.