Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GRK6 | P43250 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725410 | 0.88 | ALDH1A1 (0.72) | KAT2BALDH1A1NPSR1BCHEACHE | |
| SCHEMBL5352344 | 0.84 | ALDH1A1 (0.80) | KAT2BALDH1A1NPSR1BCHEACHE | |
| SCHEMBL7745736 | 0.84 | ALDH1A1 (0.59) | KAT2BALDH1A1NPSR1BCHEACHE | |
| SCHEMBL17678162 | 0.84 | ALDH1A1 (0.59) | KAT2BALDH1A1NPSR1BCHEACHE | |
| SCHEMBL3636228 | 0.83 | KAT2B (0.69) | KAT2BALDH1A1CYP3A4TSHRGRK6 | |
| SCHEMBL29959799 | 0.82 | ALDH1A1 (0.63) | KAT2BALDH1A1NPSR1BCHEACHE | |
| SCHEMBL14335786 | 0.82 | ALDH1A1 (0.63) | KAT2BALDH1A1NPSR1BCHEACHE | |
| SCHEMBL9725384 | 0.82 | ALDH1A1 (0.56) | KAT2BALDH1A1NPSR1BCHEACHE | |
| SCHEMBL9725555 | 0.81 | MAPT (0.56) | ALDH1A1NPSR1BCHEACHECYP3A4 | |
| SCHEMBL972656 | 0.80 | ALDH1A1 (0.65) | KAT2BALDH1A1NPSR1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486629-A | Direct dyes having a quaternary center with a long aliphatic chain | CLAIROL, INC. (US) | 1996-01-23 | — | — | US | disclosed |
| US-5360930-A | Hair dyes; shampoo stable; uniformity | CLAIROL INC. (US) | 1994-11-01 | — | — | US | disclosed |
| US-5314505-A | Hair dyes, direct dyes with improved affinity for hair | CLAIROL, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5298029-A | Hair dyes | CLAIROL INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |
| US-5256823-A | Lightfast yellow dyes | CLAIROL INCORPORATED (US) | 1993-10-26 | — | — | US | disclosed |
| US-5169403-A | Washfast hair dyes | CLAIROL, INC. | 1992-12-08 | — | — | US | disclosed |
| US-5135543-A | Lightfast blends; natural shades of yellow with sun exposure | CLAIROL INCORPORATED (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |