Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746062 | 0.89 | ALDH1A1 (0.71) | ALDH1A1NPSR1BCHEACHEKMT2A | |
| SCHEMBL8985656 | 0.84 | KAT2B (0.64) | ALDH1A1NPSR1BCHEACHEKMT2A | |
| SCHEMBL3515437 | 0.84 | HCAR3 (0.52) | ALDH1A1BCHEACHETDP1ATM | |
| SCHEMBL5352344 | 0.83 | ALDH1A1 (0.80) | ALDH1A1NPSR1BCHEACHEKMT2A | |
| SCHEMBL17678162 | 0.83 | ALDH1A1 (0.59) | ALDH1A1NPSR1BCHEACHEKMT2A | |
| SCHEMBL9725555 | 0.82 | MAPT (0.56) | ALDH1A1NPSR1BCHEACHEKMT2A | |
| SCHEMBL17845498 | 0.82 | ATM (0.51) | ALDH1A1TDP1ATMKAT2BMAPT | |
| SCHEMBL30532042 | 0.82 | ATM (0.51) | ALDH1A1TDP1ATMKAT2BMAPT | |
| SCHEMBL1283854 | 0.81 | MAPT (0.54) | ALDH1A1SMN1; SMN2TDP1ATMKAT2B | |
| SCHEMBL8200406 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KMT2ATDP1ATMKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| EP-0314162-A2 | Sulfur-containing nitroamino-benzene dyes, process and hair dye compositions | Bristol-Myers Squibb Company (US) | 1989-05-03 | — | — | EP | disclosed |
| US-4799934-A | DIRECT DYES | CLAIROL INCORPORATED (US) | 1989-01-24 | — | — | US | disclosed |