Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9760520 | 0.92 | SMN1; SMN2 (0.55) | ALDH1A1NPSR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9725417 | 0.89 | ALDH1A1 (0.67) | ALDH1A1NPSR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9759851 | 0.87 | MAPT (0.56) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL9759845 | 0.86 | MAPT (0.55) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL9725552 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NPSR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5345296 | 0.84 | ALDH1A1 (0.51) | ALDH1A1NPSR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10580319 | 0.83 | MAPT (0.58) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL10576590 | 0.83 | LMNA (0.68) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL29392855 | 0.83 | KAT2B (0.59) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL762553 | 0.83 | SMN1; SMN2 (0.60) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |