SCHEMBL5345376

SCHEMBL5345376

C[Si](C)(C)C=Cc1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.52
KDM4E B2RXH2 4/20 0.48
MAPT P10636 4/20 0.48
CA12 O43570 4/20 0.48
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA7 P43166 4/20 0.48
CA9 Q16790 4/20 0.48
CA14 Q9ULX7 4/20 0.48
TYR P14679 4/20 0.48
ALDH1A1 P00352 3/20 0.48
CYP2C9 P11712 3/20 0.48
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
CA3 P07451 3/20 0.48
CA4 P22748 3/20 0.48
CA6 P23280 3/20 0.48
CA5A P35218 3/20 0.48
CA5B Q9Y2D0 3/20 0.48
MEN1 O00255 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104736 0.78 NFE2L2 (0.50) KDM4EMAPTCA1CYP2C9LMNA
Trans-4,4'-Dihydroxystilbene SCHEMBL13339135 0.76 APP (0.74) APPKDM4EMAPTCA12CA1
Trans-4,4'-Dihydroxystilbene SCHEMBL145659 0.76 APP (0.74) APPKDM4EMAPTCA12CA1
SCHEMBL6266987 0.76 APP (0.74) APPKDM4EMAPTCA12CA1
SCHEMBL6266983 0.76 APP (0.74) APPKDM4EMAPTCA12CA1
Trans-4,4'-Dihydroxystilbene SCHEMBL491346 0.76 APP (0.74) APPKDM4EMAPTCA12CA1
SCHEMBL9678787 0.76 APP (0.74) APPKDM4EMAPTCA12CA1
SCHEMBL6266989 0.76 APP (0.74) APPKDM4EMAPTCA12CA1
SCHEMBL9678794 0.76 APP (0.74) APPKDM4EMAPTCA12CA1
SCHEMBL5845622 0.75 MAOB (0.50) KDM4EALDH1A1CYP2C9LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291692-B2 Polyarylene oxide and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-11-06 US disclosed
US-20050096452-A1 Polyarylene oxide and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 US disclosed