Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345132 | 0.89 | TACR1 (0.32) | OPRM1OPRK1 | |
| SCHEMBL5341309 | 0.88 | L3MBTL1 (0.37) | — | |
| SCHEMBL5343115 | 0.88 | POLB (0.32) | POLB | |
| SCHEMBL5344514 | 0.87 | TACR1 (0.35) | POLB | |
| SCHEMBL27550616 | 0.84 | — | — | |
| SCHEMBL5341504 | 0.80 | TACR1 (0.37) | — | |
| SCHEMBL886985 | 0.80 | KMT2A (0.35) | OPRM1OPRK1 | |
| SCHEMBL17189635 | 0.80 | — | — | |
| SCHEMBL5338623 | 0.79 | TSHR (0.46) | POLB | |
| SCHEMBL27550813 | 0.78 | CYP2D6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624306-B2 | Stabilizer for addition polymer | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | claimed |
| US-20030166939-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | NESVADBA PETER (CH) | 2003-09-04 | — | — | US | claimed |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-04-03 | — | — | US | claimed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-20050143539-A1 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | NESVADBA PETER (CH) | 2005-06-30 | — | — | US | disclosed |
| US-6624306-B2 | Stabilizer for addition polymer | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | disclosed |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166939-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | OPRM1 18/4885OPRK1 79/4885POLB 465/4885 |
| US-20050143539-A1 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | OPRM1 18/4885OPRK1 79/4885POLB 465/4885 |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | OPRM1 18/4885OPRK1 79/4885POLB 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.