Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555796 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL15720653 | 0.79 | GAA (0.33) | — | |
| SCHEMBL23857435 | 0.73 | SMYD2 (0.36) | — | |
| SCHEMBL15718081 | 0.72 | GBA1 (0.32) | — | |
| SCHEMBL2997280 | 0.71 | MEN1 (0.38) | DPP4 | |
| SCHEMBL28325239 | 0.71 | OPRK1 (0.34) | — | |
| SCHEMBL534292 | 0.69 | GBA1 (0.30) | — | |
| SCHEMBL3605608 | 0.67 | MEN1 (0.41) | — | |
| SCHEMBL20973268 | 0.67 | FKBP1A (0.31) | — | |
| SCHEMBL23931000 | 0.67 | FKBP1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413941-A1 | RENIN INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114978-A1 | RENIN INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-10-07 | — | — | WO | disclosed |