SCHEMBL5347128

SCHEMBL5347128

O=C(c1ccc2nc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)n2c1)N1CCC(N2CCCC2)CC1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 15/20 0.51
L3MBTL1 Q9Y468 14/20 0.51
MBTD1 Q05BQ5 6/20 0.51
TP53BP1 Q12888 2/20 0.51
L3MBTL4 Q8NA19 2/20 0.51
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
CNR1 P21554 1/20 0.46
LRRK2 Q5S007 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5337926 0.88 CNR1 (0.58) GABRA2GABRB2CNR1MEN1KMT2A
SCHEMBL5322233 0.88 CNR1 (0.58) GABRA2GABRB2CNR1MEN1KMT2A
SCHEMBL5345220 0.82 KDM4E (0.59) CNR1KDM4EALDH1A1KMT2A
SCHEMBL5341068 0.82 SLC2A2 (0.52) CNR1
SCHEMBL5318714 0.82 POLB (0.56) GABRA2GABRB2CNR1KDM4EALDH1A1
SCHEMBL5342501 0.82 CCNC (0.45) GABRA2GABRB2CNR1KDM4EALDH1A1
SCHEMBL5333907 0.81 CNR1 (0.53) GABRA2GABRB2CNR1KDM4EALDH1A1
SCHEMBL5341500 0.81 KMT2A (0.60) GABRA2GABRB2CNR1KMT2A
SCHEMBL5339197 0.80 CASP1 (0.49) GABRA2GABRB2CNR1KDM4EMEN1
SCHEMBL5319613 0.79 SLC2A1 (0.52) CNR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007086080-A2 NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS LIMITED (IN) 2007-08-02 WO disclosed