Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.57 |
| ▸ | CTSL | P07711 | 5/20 | 0.57 |
| ▸ | CTSB | P07858 | 4/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24736349 | 0.85 | CTSS (0.57) | CTSSCTSLCTSBTLR2CTSK | |
| SCHEMBL8234255 | 0.82 | CTSS (0.53) | CTSSCTSLCTSBCTSKMMP1 | |
| SCHEMBL2704426 | 0.82 | CTSS (0.52) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL20179421 | 0.77 | CTSS (0.50) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL9293928 | 0.76 | LMNA (0.59) | CTSSCTSLCTSBCTSKHSD17B10 | |
| SCHEMBL7943021 | 0.75 | CTSS (0.57) | CTSSCTSLCTSBTLR2CTSK | |
| SCHEMBL6181261 | 0.75 | CTSS (0.89) | CTSSCTSLCTSBCTSK | |
| SCHEMBL10239127 | 0.75 | CTSL (0.47) | CTSSCTSLCTSBATM | |
| SCHEMBL1508888 | 0.74 | CTSS (0.56) | CTSSCTSLCTSBTLR2CTSK | |
| SCHEMBL1508675 | 0.74 | CTSS (0.56) | CTSSCTSLCTSBTLR2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007110727-A2 | AMIDE STABILIZED HYDROXYETHYLAMINES | PFIZER PRODUCTS INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007110727-A2 | AMIDE STABILIZED HYDROXYETHYLAMINES | PFIZER PRODUCTS INC. (US) | 2007-10-04 | — | — | WO | disclosed |