Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18872367 | 0.86 | PTPN1 (0.53) | TAS2R38HSD17B10NAPRTMAPTALDH1A1 | |
| SCHEMBL19825999 | 0.86 | SMN1; SMN2 (0.46) | TAS2R38HSD17B10NAPRTMAPTALDH1A1 | |
| SCHEMBL15743709 | 0.83 | TAS2R38 (0.52) | TAS2R38HSD17B10NAPRTMAPTALDH1A1 | |
| SCHEMBL18473288 | 0.81 | MGLL (0.61) | NPC1RAB9ASMN1; SMN2TSHRKMT2A | |
| SCHEMBL19263968 | 0.81 | HPGD (0.61) | MAPTALDH1A1NPC1RAB9AEPHX1 | |
| SCHEMBL14301712 | 0.80 | TAS2R38 (0.54) | TAS2R38HSD17B10NAPRTMAPTALDH1A1 | |
| SCHEMBL14347597 | 0.78 | TAS2R38 (0.64) | TAS2R38HSD17B10NAPRTMAPTALDH1A1 | |
| SCHEMBL14347590 | 0.78 | TAS2R38 (0.64) | TAS2R38HSD17B10NAPRTMAPTALDH1A1 | |
| SCHEMBL8151745 | 0.78 | HSD17B10 (0.55) | TAS2R38HSD17B10NAPRTALDH1A1NPC1 | |
| SCHEMBL22100361 | 0.78 | HSD17B10 (0.55) | TAS2R38HSD17B10NAPRTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484472-A | A kind of synthetic method of thioindole quinoline class compound | 华中科技大学 | 2018-09-04 | — | — | CN | claimed |
| CN-100402610-C | Dye mixtures, their preparation method and their use | CIBA SPECILITY CHEMICALS HOLDI (CH) | 2008-07-16 | — | — | CN | claimed |
| CN-1097076-C | Active dye, their preparation and use | CIBA SPECIALTY CHEMICALS HOLSI (CH) | 2002-12-25 | — | — | CN | claimed |
| CN-1350036-A | Dye mixtures, their preparation method and their use | CIBA SPECILITY CHEMICALS HOLDI (CH) | 2002-05-22 | — | — | CN | claimed |
| CN-1058012-C | Reactive dyes from dioxazine series, their preparation and use | CIBA SC HOLDING AG (CH) | 2000-11-01 | — | — | CN | claimed |
| CN-1163291-A | Active dye, their preparation and use | CIBA GEIGY AG (CH) | 1997-10-29 | — | — | CN | claimed |
| CN-1146468-A | Dye mixtures, process for their preparation and their use | CIBA GEIGY AG (CH) | 1997-04-02 | — | — | CN | claimed |
| CN-1142500-A | Reactive dyes from dioxazine series, their preparation and use | CIBA GEIGY AG (CH) | 1997-02-12 | — | — | CN | claimed |
| CN-1104227-A | Reactive dyes, their preparation and their use | CIBA GEIGY AG (CH) | 1995-06-28 | — | — | CN | claimed |
| JP-61282349-A | — | — | None | — | — | JP | disclosed |
| JP-2024316-A | — | — | None | — | — | JP | disclosed |
| JP-3021616-A | — | — | None | — | — | JP | disclosed |
| JP-56131566-A | — | — | None | — | — | JP | disclosed |
| US-12528916-B2 | Transmembrane pH-gradient polymersomes | ETH ZURICH (CH) | 2026-01-20 | — | — | US | disclosed |
| EP-0099516-A1 | Process for the preparation of bis(aminocyclohexyl)dialkyl methanes | BASF Aktiengesellschaft (DE) | 1984-02-01 | — | — | EP | disclosed |
| US-4401777-A | Curable resin composition comprising N-(alkenylphenyl)maleimide and epoxy composition | MITSUI TOATSU CHEMICALS, INC. (JP) | 1983-08-30 | — | — | US | disclosed |
| EP-0077840-A1 | Curable resin composition | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1983-05-04 | — | — | EP | disclosed |
| US-4323662-A | Thermosetting resin compositions comprising bismaleimides and alkenylaniline derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-04-06 | — | — | US | disclosed |
| JP-S56131566-A | MALEIMIDE DERIVATIVE AND ITS PREPARATION | MITSUI TOATSU CHEM INC | 1981-10-15 | — | — | JP | disclosed |
| US-4156757-A | Electrically conductive perylene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528916-B2 | Transmembrane pH-gradient polymersomes | AQP4, ABCB11, SLC6A6 | TAS2R38 110/4885HSD17B10 2121/4885NAPRT 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.