SCHEMBL162169

SCHEMBL162169

COC(=O)c1c(Cl)c(Cl)c(C(=O)O)c(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 3/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 4/20 0.38
LMNA P02545 3/20 0.38
NR4A2 P43354 1/20 0.38
NPSR1 Q6W5P4 2/20 0.37
CYP3A4 P08684 1/20 0.35
ACHE P22303 1/20 0.35
GLA P06280 1/20 0.35
HPGD P15428 1/20 0.35
HSP90B1 P14625 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dacthal SCHEMBL8539721 1.00 CA12 (0.41) CA12CA1CA2CA7CA9
Dacthal SCHEMBL53477 0.90 CA12 (0.48) CA12CA1CA2CA7CA9
Dacthal SCHEMBL8827292 0.90 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL5336516 0.88 CA12 (0.40) CA12CA1CA2CA7CA9
SCHEMBL8339188 0.87 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL7202434 0.85 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL5334826 0.82 CA12 (0.46) CA12CA1CA2CA7CA9
Dacthal SCHEMBL11248678 0.82 TSHR (0.43) CA12CA1CA2CA7CA9
SCHEMBL11696970 0.81 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL12921185 0.81 KDM4E (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 720 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-4337017-A1 HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS Bayer Aktiengesellschaft (DE) 2024-03-20 EP claimed
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2023-01-05 US claimed
WO-2022152728-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2022-07-21 WO claimed
US-20210378241-A1 COMBINATION COMPRISING A BENZAMIDE HERBICIDE AND A PYRIDINE CARBOXYLIC ACID HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2021-12-09 US claimed
EP-3174865-B1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-12-09 EP claimed
WO-2020154349-A1 METHODS AND FORMULATIONS FOR PREVENTING DOWNWARD MIGRATION OF AGRICULTURAL MATERIALS BAYER CROPSCIENCE LP (US) 2020-07-30 WO claimed
US-20200236925-A1 METHODS AND FORMULATIONS FOR PREVENTING DOWNWARD MIGRATION OF AGRICULTURAL MATERIALS DISCOVERY PURCHASER CORPORATION 2020-07-30 US claimed
US-RE48057-E1 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2020-06-23 US claimed
US-20200055846-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-02-20 US claimed
WO-2012154533-A2 CONTROLLING PLANTHOPPERS DOW AGROSCIENCES LLC (US) 2012-11-15 WO claimed
WO-2012154537-A1 CONTROLLING PLANTHOPPERS DOW AGROSCIENCES LLC (US) 2012-11-15 WO claimed
US-20120283100-A1 CONTROLLING PLANTHOPPERS DOW AGROSCIENCES LLC (US) 2012-11-08 US claimed
US-20120283099-A1 CONTROLLING PLANTHOPPERS DOW AGROSCIENCES LLC (US) 2012-11-08 US claimed
US-20120195974-A1 CONTROLLING MEALYBUGS DOW AGROSCIENCES LLC (US) 2012-08-02 US claimed
WO-2012103393-A2 CONTROLLING MEALYBUGS DOW AGROSCIENCES LLC (US) 2012-08-02 WO claimed
WO-2012061290-A2 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-10 WO claimed
WO-2012061288-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-10 WO claimed
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-03 US claimed
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto CORTEVA AGRISCIENCE LLC 2012-05-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, TDO2, DNTT CA12 4073/4885CA1 2228/4885CA2 1364/4885
US-20210378241-A1 COMBINATION COMPRISING A BENZAMIDE HERBICIDE AND A PYRIDINE CARBOXYLIC ACID HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, GAP43, PDHA2 CA12 2914/4885CA1 2695/4885CA2 1814/4885
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, AGPS, DDT CA12 2201/4885CA1 876/4885CA2 162/4885
US-20200055846-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS CA12 2459/4885CA1 982/4885CA2 210/4885
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto ACHE, DDT, PTMS CA12 2459/4885CA1 982/4885CA2 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.