Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | IAPP | P10997 | 3/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351263 | 0.87 | GABRA1 (0.37) | GABRA1GABRB2CYP2D6CYP2C19KDM4E | |
| SCHEMBL5346793 | 0.84 | ALOX5 (0.44) | GABRA1GABRB2CYP2D6CYP2C19KDM4E | |
| SCHEMBL5348955 | 0.83 | ALOX5 (0.50) | KDM4EMAPTHSD17B10ELANEIAPP | |
| SCHEMBL5346129 | 0.82 | ALOX5 (0.49) | KDM4EMEN1CYP3A4MAPTTSHR | |
| SCHEMBL2809244 | 0.77 | ALDH1A1 (0.48) | GABRA1GABRB2CYP2D6CYP2C19KDM4E | |
| SCHEMBL4307952 | 0.75 | KDM4E (0.39) | CYP2D6CYP2C19KDM4EMEN1ALDH1A1 | |
| SCHEMBL11230027 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL20945362 | 0.73 | KDM4E (0.43) | CYP2D6CYP2C19KDM4EMEN1ALDH1A1 | |
| SCHEMBL29791106 | 0.73 | KDM4E (0.43) | CYP2D6CYP2C19KDM4EMEN1ALDH1A1 | |
| SCHEMBL199730 | 0.72 | GABRA1 (1.00) | GABRA1GABRB2IAPPPTPN5DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291692-B2 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20050096452-A1 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |