SCHEMBL5350067

SCHEMBL5350067

CC(=O)Nc1cc(-n2nc(C)n(C(F)F)c2=O)c(Cl)cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.69
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfentrazone SCHEMBL18489655 0.81 PPOX (1.00) PPOX
SCHEMBL13528799 0.81 PPOX (0.67) PPOX
SCHEMBL5417601 0.80 PPOX (0.60) PPOX
SCHEMBL10566446 0.79 PPOX (0.62) PPOX
SCHEMBL9631537 0.78 PPOX (0.63) PPOX
Sulfentrazone SCHEMBL1665487 0.77 PPOX (0.80) PPOXKMT2A
Hydrochloric Acid SCHEMBL8474410 0.77 PPOX (0.62) PPOX
SCHEMBL19741457 0.76 PPOX (0.61) PPOX
SCHEMBL9631108 0.76 PPOX (0.60) PPOXKDM4EALDH1A1HTTRAB9A
SCHEMBL10565477 0.75 PPOX (0.54) PPOXKDM4EALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315744-B In the sulfenamide Synthesis method of intermediate 浙大宁波理工学院 2024-09-13 CN claimed
CN-114181162-B Preparation method of sulfonyl carfentrazone-ethyl 浙大宁波理工学院 2024-04-16 CN claimed
CN-114057659-B Intermediate for synthesizing sulfenamide and synthesis method thereof 浙大宁波理工学院 2024-03-26 CN claimed
CN-114044758-B Synthetic method of intermediate for preparing triazolinone herbicide sulfenamide 浙大宁波理工学院 2024-03-26 CN claimed
CN-114315744-A Synthetic method of sulfentrazone intermediate 浙大宁波理工学院 2022-04-12 CN claimed
CN-114276306-A Synthetic method of sulfentrazone 浙大宁波理工学院 2022-04-05 CN claimed
CN-114181162-A Preparation method of sulcarfentrazone-ethyl 浙大宁波理工学院 2022-03-15 CN claimed
CN-114057659-A Intermediate for synthesizing sulfentrazone and synthesis method thereof 浙大宁波理工学院 2022-02-18 CN claimed
CN-114044758-A Synthesis method of intermediate for preparing triazolinone herbicide sulfentrazone 浙大宁波理工学院 2022-02-15 CN claimed
US-7169952-B2 Process to prepare sulfonamides FMC CORPORATION (US) 2007-01-30 US claimed
US-20030236437-A1 Process to prepare sulfonamides FMC CORPORATION 2003-12-25 US claimed
CN-114315744-B In the sulfenamide Synthesis method of intermediate 浙大宁波理工学院 2024-09-13 CN disclosed
CN-118290299-A 2- (2- (5-Acetamido-2, 4-dichlorophenyl) hydrazono) propionic acid compound 浙大宁波理工学院 2024-07-05 CN disclosed
CN-118084716-A N- (2, 4-dichloro-5-hydrazinophenyl) acetamide compound 浙大宁波理工学院 2024-05-28 CN disclosed
CN-114181162-B Preparation method of sulfonyl carfentrazone-ethyl 浙大宁波理工学院 2024-04-16 CN disclosed
CN-114057659-A Intermediate for synthesizing sulfentrazone and synthesis method thereof 浙大宁波理工学院 2022-02-18 CN disclosed
CN-114044758-A Synthesis method of intermediate for preparing triazolinone herbicide sulfentrazone 浙大宁波理工学院 2022-02-15 CN disclosed
US-7169952-B2 Process to prepare sulfonamides FMC CORPORATION (US) 2007-01-30 US disclosed
US-20030236437-A1 Process to prepare sulfonamides FMC CORPORATION 2003-12-25 US disclosed
WO-2001094320-A2 PROCESS TO PREPARE SULFONAMIDES FMC CORPORATION (US) 2001-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236437-A1 Process to prepare sulfonamides SULT2A1, SULT1A1, SRM PPOX 1159/4885KDM4E 1420/4885NPC1 4240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.