Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.58 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766101 | 0.87 | PPARA (0.59) | TAOK1TAOK3SIRT2SIRT1CTSL | |
| SCHEMBL1447017 | 0.87 | PPARA (0.59) | TAOK1TAOK3SIRT2SIRT1CTSL | |
| SCHEMBL7104052 | 0.81 | CTSS (0.72) | S1PR1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL15569270 | 0.80 | CTSS (0.57) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL7766094 | 0.79 | CTSL (0.50) | SIRT2SIRT1CTSLCTSS | |
| SCHEMBL15156902 | 0.79 | SIRT2 (0.54) | SIRT2SIRT1CTSLCTSS | |
| SCHEMBL7766108 | 0.79 | CTSL (0.50) | SIRT2SIRT1CTSLCTSS | |
| SCHEMBL13911921 | 0.78 | CTSK (0.58) | CTSLCTSS | |
| SCHEMBL31030159 | 0.78 | CTSK (0.48) | TAOK1TAOK3CTSLCTSS | |
| SCHEMBL1375817 | 0.78 | S1PR1 (0.64) | TAOK1TAOK3S1PR1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166590-B2 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | TAOK1 837/4885TAOK3 797/4885SIRT2 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.