Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.50 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447017 | 1.00 | PPARA (0.59) | PPARAFOLH1PPARGCTSLCTSS | |
| SCHEMBL15156902 | 0.91 | SIRT2 (0.54) | PPARAFOLH1CTSLCTSSMME | |
| SCHEMBL12879969 | 0.90 | CTSL (0.57) | PPARACTSLCTSSCTSKSIRT2 | |
| SCHEMBL16582478 | 0.90 | CTSL (0.57) | PPARACTSLCTSSCTSKSIRT2 | |
| SCHEMBL7766108 | 0.89 | CTSL (0.50) | PPARACTSLCTSSCTSKSIRT2 | |
| SCHEMBL7766094 | 0.89 | CTSL (0.50) | PPARACTSLCTSSCTSKSIRT2 | |
| SCHEMBL5350193 | 0.87 | TAOK1 (0.58) | CTSLCTSSTAOK1TAOK3SIRT2 | |
| SCHEMBL8457371 | 0.86 | SIRT2 (0.53) | PPARAFOLH1CTSLCTSSMME | |
| SCHEMBL6663760 | 0.86 | PPARA (0.44) | PPARAFOLH1PPARGCTSLCTSS | |
| SCHEMBL1024175 | 0.85 | PPARA (0.64) | PPARAFOLH1PPARGCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100814-A2 | INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000005245-A2 | INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2000-02-03 | — | — | WO | disclosed |
| US-3971737-A | [2-Methyl-Ala6 ]LRH | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |