SCHEMBL5350442

SCHEMBL5350442

N[C@@H](C=O)[C@@H](OC(=O)C(O)c1ccccc1)[C@H](O)[C@H](O)CO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.36
LMNA P02545 4/20 0.36
MAPK1 P28482 1/20 0.36
PRKCA P17252 1/20 0.34
CYP2D6 P10635 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP1A2 P05177 1/20 0.33
PKM P14618 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP2C9 P11712 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GRM2 Q14416 1/20 0.32
GRM3 Q14832 1/20 0.32
CHRM2 P08172 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9807657 0.77 USP2 (0.43) LMNAUSP2SLCO1B1TDP1
SCHEMBL9807660 0.77 USP2 (0.43) LMNAUSP2SLCO1B1TDP1
SCHEMBL2159077 0.77 PAX8 (0.36) USP2SLCO1B1
SCHEMBL17767377 0.76 PAX8 (0.41) LMNAUSP2SLCO1B1
SCHEMBL1788963 0.76 PAX8 (0.41) LMNAUSP2SLCO1B1
SCHEMBL16429713 0.76 USP2 (0.38) LMNAUSP2SLCO1B1TDP1
SCHEMBL5354996 0.76 USP2 (0.38) LMNAUSP2SLCO1B1TDP1
SCHEMBL970995 0.76 TDP1 (0.38) LMNAPRKCASMN1; SMN2KMT2AALDH1A1
SCHEMBL2842689 0.75 USP2 (0.37) LMNAUSP2SLCO1B1TDP1
SCHEMBL3180833 0.74 EPHX1 (0.45) LMNACYP2C9CHRM1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170360687-A1 SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF L'OREAL (FR) 2017-12-21 US claimed
EP-3236922-A1 SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF L'OREAL (FR) 2017-11-01 EP claimed
WO-2016102702-A1 SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF L'OREAL (FR) 2016-06-30 WO claimed
US-20040228884-A1 Ion-pair delivery system for cosmetic and pharmaceutical compositions GUPTA SHYAM K (US) 2004-11-18 US claimed
US-20040156873-A1 Topically Bioavailable Acne and Rosacea Treatment Compositions GUPTA SHYAM K (US) 2004-08-12 US claimed
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions GUPTA SHYAM K (US) 2004-05-13 US claimed
US-20170360687-A1 SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF L'OREAL (FR) 2017-12-21 US disclosed
EP-3236922-A1 SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF L'OREAL (FR) 2017-11-01 EP disclosed
WO-2016102702-A1 SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF L'OREAL (FR) 2016-06-30 WO disclosed
US-7179477-B2 Cosmetic dermabrasion treatment system GUPTA SHYAM K 2007-02-20 US disclosed
WO-2006023710-A2 COSMETIC OR PHARMACEUTICAL COMPOSITION FOR SKIN CARE INFINITY2 HEALTH SCIENCES, INC. (US) 2006-03-02 WO disclosed
US-20060039887-A1 Cosmetic or pharmaceutical composition for skin care INFINITY2 HEALTH SCIENCES, INC. 2006-02-23 US disclosed
US-20050037038-A1 Cosmetic Dermabrasion Treatment System GUPTA SHYAM K (US) 2005-02-17 US disclosed
US-20040228884-A1 Ion-pair delivery system for cosmetic and pharmaceutical compositions GUPTA SHYAM K (US) 2004-11-18 US disclosed
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions GUPTA SHYAM K (US) 2004-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions CUTA, HIRA, HARS1 KIF11 3362/4885LMNA 736/4885MAPK1 4151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.