Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350983 | 1.00 | MAPT (0.43) | MAPTTHRBCFTRCNR2S1PR3 | |
| SCHEMBL5427985 | 0.86 | CCR2 (0.43) | MAPTMTNR1AMTNR1B | |
| SCHEMBL5427991 | 0.86 | CCR2 (0.43) | MAPTMTNR1AMTNR1B | |
| SCHEMBL5359096 | 0.85 | CCR2 (0.49) | MAPTHDAC1HDAC6KMT2AKDM4E | |
| SCHEMBL5363418 | 0.85 | CCR2 (0.49) | MAPTHDAC1HDAC6KMT2AKDM4E | |
| SCHEMBL5372569 | 0.82 | SRD5A2 (0.43) | S1PR3ACSS2KMT2AKDM4EMTNR1A | |
| SCHEMBL5369798 | 0.82 | SRD5A2 (0.43) | S1PR3ACSS2KMT2AKDM4EMTNR1A | |
| SCHEMBL5358101 | 0.79 | FDPS (0.40) | MAPTKMT2AKDM4ESMN1; SMN2NR1H4 | |
| SCHEMBL5358104 | 0.79 | FDPS (0.40) | MAPTKMT2AKDM4ESMN1; SMN2NR1H4 | |
| SCHEMBL5362181 | 0.76 | MEN1 (0.42) | MAPTKMT2AKDM4ESMN1; SMN2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |