Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359096 | 1.00 | CCR2 (0.49) | CCR2HDAC6HDAC10SRCNOD2 | |
| SCHEMBL5427991 | 0.89 | CCR2 (0.43) | CCR2HTTMAPTBRD4 | |
| SCHEMBL5427985 | 0.89 | CCR2 (0.43) | CCR2HTTMAPTBRD4 | |
| SCHEMBL5358104 | 0.85 | FDPS (0.40) | CCR2KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5358101 | 0.85 | FDPS (0.40) | CCR2KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5350983 | 0.85 | MAPT (0.43) | HDAC6KMT2AKDM4EHDAC1ALDH1A1 | |
| SCHEMBL5350992 | 0.85 | MAPT (0.43) | HDAC6KMT2AKDM4EHDAC1ALDH1A1 | |
| SCHEMBL5369798 | 0.85 | SRD5A2 (0.43) | KMT2AKDM4EHDAC8ALDH1A1PPARG | |
| SCHEMBL5372569 | 0.85 | SRD5A2 (0.43) | KMT2AKDM4EHDAC8ALDH1A1PPARG | |
| SCHEMBL5362181 | 0.84 | MEN1 (0.42) | CCR2KMT2AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |