Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CCR9 | P51686 | 6/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HK1 | P19367 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5427991 | 1.00 | CCR2 (0.43) | CCR2CD74MIFGNRHRBRD4 | |
| SCHEMBL5363418 | 0.89 | CCR2 (0.49) | CCR2BRD4MAPTHTT | |
| SCHEMBL5359096 | 0.89 | CCR2 (0.49) | CCR2BRD4MAPTHTT | |
| SCHEMBL5369798 | 0.86 | SRD5A2 (0.43) | CCR9MTNR1AMTNR1B | |
| SCHEMBL5350992 | 0.86 | MAPT (0.43) | MTNR1AMTNR1BMAPT | |
| SCHEMBL5372569 | 0.86 | SRD5A2 (0.43) | CCR9MTNR1AMTNR1B | |
| SCHEMBL5350983 | 0.86 | MAPT (0.43) | MTNR1AMTNR1BMAPT | |
| SCHEMBL5358104 | 0.82 | FDPS (0.40) | CCR2BRD4MAPT | |
| SCHEMBL5358101 | 0.82 | FDPS (0.40) | CCR2BRD4MAPT | |
| SCHEMBL5362181 | 0.79 | MEN1 (0.42) | CCR2BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |