SCHEMBL5351065

SCHEMBL5351065

COc1ccc(-n2c(=O)[nH]c3cc(N)ccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.52
KMT2A Q03164 3/20 0.52
ALDH1A1 P00352 5/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 3/20 0.46
MEN1 O00255 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HPGD P15428 3/20 0.45
KDM4E B2RXH2 3/20 0.44
TP53 P04637 1/20 0.44
NTRK1 P04629 1/20 0.43
IGF1R P08069 1/20 0.43
FGFR1 P11362 1/20 0.43
NTRK2 Q16620 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HRH3 Q9Y5N1 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5718492 0.84 ALDH1A1 (0.50) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL4934267 0.82 ATM (0.54) ATMKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL5353986 0.81 MEN1 (0.64) ATMKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL5718587 0.81 MEN1 (0.68) KMT2AALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL11346077 0.80 ATM (0.57) ATMKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL6002037 0.80 ALDH1A1 (0.68) ATMKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL6002533 0.79 CTSV (0.53) ATMKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL17477674 0.77 MAPT (0.54) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL7843289 0.77 TSHR (0.45) KMT2AALDH1A1MAPTLMNAMEN1
SCHEMBL11314421 0.76 MAPT (0.48) KMT2AALDH1A1MAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670486-A Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety CIBA-GEIGY CORPORATION (US) 1987-06-02 US claimed
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
EP-0889046-B1 Triphendioxazines and their use as pigments CLARIANT FINANCE BVI LTD (VG) 2005-08-31 EP disclosed
EP-1517962-A1 METHOD FOR PRODUCING DISAZO PIGMENTS Clariant GmbH (DE) 2005-03-30 EP disclosed
WO-2004000947-A1 METHOD FOR PRODUCING DISAZO PIGMENTS CLARIANT GMBH (DE) 2003-12-31 WO disclosed
US-6162261-A Triphendioxazine CLARIANT FINANCE (BVI) LIMITED (VG) 2000-12-19 US disclosed
EP-0889046-A1 Triphendioxazines and their use as pigments Clariant Finance (BVI) Limited (VG) 1999-01-07 EP disclosed
EP-0168343-B1 METAL COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING HIGH-MOLECULAR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1991-05-02 EP disclosed
EP-0169167-B1 PROCESS FOR DYEING HIGH-MOLECULAR ORGANIC MATERIALS, AND METAL COMPLEXES CIBA-GEIGY AG (CH) 1990-05-02 EP disclosed
US-4263205-A FOR COLORING POLYMERS, LACQUERS CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
US-4229344-A Monazo pigments containing hydroxynaphthoylaminobenzimidazalone radical CIBA-GEIGY CORPORATION (US) 1980-10-21 US disclosed
US-4220586-A FASTNESS TO LIGHT, OVER-LACQUERING, MIGRATION, WEATHERING, AND HEAT CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
US-4116959-A ISOINDOLINE PIGMENTS CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4088641-A YELLOW TO RED SHADES CIBA-GEIGY CORPORATION (US) 1978-05-09 US disclosed
US-4052410-A YELLOW, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1977-10-04 US disclosed
US-4012371-A Benzinaldazolyl-, quinolonyl-, or phenmorpholonylazo-3-cyano-4-methyl-1,2-[1',2']-benz-[4',5']-imidazolo-6-hydroxypyridine colorants CIBA-GEIGY CORPORATION (US) 1977-03-15 US disclosed
US-3979386-A YELLOW, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1976-09-07 US disclosed
US-3963694-A AZO PIGMENTS, POLYESTERS, CELLULOSE ETHERS AND ESTERS CIBA-GEIGY CORPORATION (US) 1976-06-15 US disclosed
US-3956266-A DISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 ATM 4434/4885KMT2A 2138/4885ALDH1A1 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.