Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 3/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.43 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491527 | 0.80 | ERCC1 (0.71) | AOC3ERCC1ERCC4PADI1PADI3 | |
| SCHEMBL5363722 | 0.80 | AOC3 (0.49) | AOC3ERAP2ERAP1LNPEPERCC1 | |
| SCHEMBL13066398 | 0.76 | KMT2A (0.56) | CCR2 | |
| SCHEMBL18638228 | 0.74 | ERAP2 (0.67) | AOC3ERAP2ERAP1LNPEPERCC1 | |
| SCHEMBL7106098 | 0.74 | OPRK1 (0.53) | ERCC1ERCC4CCR2 | |
| SCHEMBL14365887 | 0.73 | AOC3 (0.63) | AOC3ERAP2ERAP1LNPEPPSMB1 | |
| SCHEMBL6418674 | 0.72 | AOC3 (0.67) | AOC3ERAP2ERAP1LNPEPPADI1 | |
| SCHEMBL18602713 | 0.72 | ERAP2 (0.64) | AOC3ERAP2ERAP1LNPEPERCC1 | |
| SCHEMBL5357017 | 0.72 | MTNR1A (0.54) | — | |
| SCHEMBL6231852 | 0.71 | AOC3 (0.57) | AOC3ERAP2ERAP1LNPEPPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202253-B2 | Cycloalkyl inhibitors of potassium channel function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202253-B2 | Cycloalkyl inhibitors of potassium channel function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202253-B2 | Cycloalkyl inhibitors of potassium channel function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-10 | — | — | US | disclosed |