Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103185 | 0.89 | OPRK1 (0.54) | OPRK1OPRD1MMP1MMP2MMP9 | |
| SCHEMBL7103456 | 0.82 | OPRK1 (0.42) | OPRK1OPRD1LMNA | |
| SCHEMBL5351192 | 0.74 | AOC3 (0.50) | ERCC1ERCC4CCR2 | |
| SCHEMBL7106093 | 0.70 | ERCC1 (0.48) | ERCC1ERCC4MMP1MMP2MMP9 | |
| SCHEMBL7106096 | 0.70 | ERCC1 (0.42) | OPRK1OPRD1ERCC1ERCC4MMP1 | |
| SCHEMBL7102313 | 0.69 | OPRK1 (1.00) | OPRK1OPRD1MMP1MMP2MMP9 | |
| SCHEMBL1525284 | 0.69 | SMN1; SMN2 (0.54) | ERCC1ERCC4MMP8SMN1; SMN2MEN1 | |
| SCHEMBL4388189 | 0.69 | ERCC1 (0.53) | ERCC1ERCC4MMP8SMN1; SMN2MEN1 | |
| SCHEMBL17107769 | 0.68 | MMP8 (0.55) | ERCC1ERCC4MMP8SMN1; SMN2MEN1 | |
| SCHEMBL7435493 | 0.67 | MMP8 (0.57) | ERCC1ERCC4MMP8SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |