Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297716 | 0.90 | ALDH1A1 (0.43) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL9198448 | 0.83 | ALDH1A1 (0.48) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL29938143 | 0.83 | ALDH1A1 (0.48) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL2994229 | 0.83 | ALDH1A1 (0.48) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL30750882 | 0.83 | TSHR (0.56) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL2059016 | 0.83 | TSHR (0.56) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL25908466 | 0.81 | ALDH1A1 (0.50) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL7099525 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL28297714 | 0.80 | ALDH1A1 (0.45) | ALDH1A1PDE10ATSHRGAAGLA | |
| SCHEMBL21496127 | 0.77 | ALDH1A1 (0.42) | ALDH1A1PDE10ATSHRGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187883-B | Quinoline compound containing perfluoroalkyl substituent group, preparation method and application thereof | 浙江省化工研究院有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-7169955-B2 | Perfluoroisopropylbenzene derivative | NIHON NOHYAKU CO., LTD. (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-1006102-B1 | Process for the production of perfluoroalkylated aniline derivatives | NIHON NOHYAKU CO LTD (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20050113567-A1 | Perfluoroisopropylbenzene derivative | NIHON NOHYAKU CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| US-6717013-B2 | EASILY ATTAINED WITH HIGH POSITIONAL SELECTIVITY AND YIELD; INTERMEDIATES AND RAW MATERIALS | NIHON NOHYAKU CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| EP-1380568-A2 | Perfluoroalkylaniline derivatives | NIHON NOHYAKU CO., LTD. (JP) | 2004-01-14 | — | — | EP | disclosed |
| US-20030204104-A1 | Perfluoroalkylated aniline compound and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2003-10-30 | — | — | US | disclosed |
| US-20030187233-A1 | PERFLUOROISOPROPYBENZENE DERIVATIVE | NIHON NOHYAKU CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| US-6600074-B2 | Useful as intermediates or raw materials for the synthesis of agricultural chemicals, pharmaceuticals | NIHON NOHYAKU CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| US-20020198399-A1 | Perfluoroalkylated aniline compound and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1253128-A1 | PERFLUOROISOPROPYLBENZENE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2002-10-30 | — | — | EP | disclosed |
| EP-1006102-A2 | Aniline derivative and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2000-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187233-A1 | PERFLUOROISOPROPYBENZENE DERIVATIVE | AFF1, CBR1, RER1 | ALDH1A1 1079/4885PDE10A 4330/4885TSHR 232/4885 |
| US-20020198399-A1 | Perfluoroalkylated aniline compound and process for producing the same | CYP8B1, CCR8, AFF1 | ALDH1A1 722/4885PDE10A 3377/4885TSHR 228/4885 |
| US-20050113567-A1 | Perfluoroisopropylbenzene derivative | FFAR3, CBR3, HCAR3 | ALDH1A1 2953/4885PDE10A 3164/4885TSHR 60/4885 |
| US-20030204104-A1 | Perfluoroalkylated aniline compound and process for producing the same | CYP8B1, CCR8, AFF1 | ALDH1A1 722/4885PDE10A 3377/4885TSHR 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.