Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30750882 | 0.84 | TSHR (0.56) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL2059016 | 0.84 | TSHR (0.56) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL12024599 | 0.83 | ALDH1A1 (0.50) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL14803471 | 0.82 | ALDH1A1 (0.54) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL3006494 | 0.82 | ALDH1A1 (0.54) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL29938143 | 0.81 | ALDH1A1 (0.48) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL5351652 | 0.81 | ALDH1A1 (0.48) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL9198448 | 0.81 | ALDH1A1 (0.48) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL2994229 | 0.81 | ALDH1A1 (0.48) | ALDH1A1PDE10AL3MBTL1TSHRGAA | |
| SCHEMBL31481037 | 0.78 | KIF11 (0.50) | ALDH1A1TSHRGAAPOLBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234925-A1 | GPR52 MODULATORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234925-A1 | GPR52 MODULATORS AND METHODS OF USE | GPR52, GPR68, GPR35 | ALDH1A1 1831/4885PDE10A 533/4885L3MBTL1 4858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.