Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300954 | 0.77 | ALOX15 (0.48) | PAMKMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL5547366 | 0.74 | KDM4E (0.44) | PAMPKMKMT2ASMN1; SMN2 | |
| SCHEMBL27429691 | 0.71 | GRIK1 (0.43) | GABBR2GABBR1GRIK1GRIK2LTA4H | |
| SCHEMBL27301184 | 0.71 | SLC15A1 (0.54) | LTA4HSLC15A1ALPIPKMPTGS1 | |
| SCHEMBL7065850 | 0.71 | SLC15A1 (0.54) | LTA4HSLC15A1ALPIPKMPTGS1 | |
| SCHEMBL28379498 | 0.71 | SLC15A1 (0.54) | LTA4HSLC15A1ALPIPKMPTGS1 | |
| SCHEMBL5413773 | 0.71 | PTGDR2 (0.66) | CASP1KMT2ASMN1; SMN2 | |
| Aspartic Acid SCHEMBL23242572 | 0.70 | GRIK1 (0.53) | GRIK1GRIK2ALPIPKMPTGS1 | |
| SCHEMBL6810004 | 0.69 | GRIK1 (0.47) | GABBR2GABBR1GRIK1GRIK2LTA4H | |
| SCHEMBL7384196 | 0.68 | POLB (0.43) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414371-A2 | HEPARAN SULFATE SYNTHESIS | The University Of Georgia Research Foundation, Inc (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010117803-A2 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-10-14 | — | — | WO | disclosed |