Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727816 | 0.81 | PTPN1 (0.38) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3300954 | 0.80 | ALOX15 (0.48) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27087365 | 0.79 | AKT1 (0.46) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12493341 | 0.78 | TSHR (0.47) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL5547366 | 0.77 | KDM4E (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL5410674 | 0.74 | TRPA1 (0.39) | ALDH1A1MEN1KMT2ATSHR | |
| Benzophenone SCHEMBL28414451 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL290049 | 0.73 | POLB (0.46) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2363130 | 0.73 | GPR174 (0.38) | ALDH1A1MEN1KMT2AMAPTRECQL | |
| SCHEMBL27303351 | 0.73 | MEN1 (0.62) | POLBALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994896-A1 | SULFONYLATED DIPEPTIDE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-04-26 | — | — | EP | claimed |
| WO-1999006437-A1 | SULFONYLATED DIPEPTIDE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS INC. (US) | 1999-02-11 | — | — | WO | claimed |