Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 8/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351314 | 0.84 | GPR119 (0.46) | GAAEPHX1DRD2KCNA3 | |
| SCHEMBL3612235 | 0.75 | CTSS (0.48) | GAAEPHX1CA1CTSKHDAC4 | |
| SCHEMBL19744962 | 0.75 | EPHX1 (0.43) | GAAEPHX1CA2CTSKHDAC4 | |
| SCHEMBL3612229 | 0.75 | CTSS (0.48) | GAAEPHX1CA1CTSKHDAC4 | |
| SCHEMBL3610831 | 0.74 | EPHX1 (0.43) | GAAEPHX1CTSKHDAC4HDAC1 | |
| SCHEMBL3610835 | 0.74 | EPHX1 (0.43) | GAAEPHX1CTSKHDAC4HDAC1 | |
| SCHEMBL5351867 | 0.74 | HDAC4 (0.47) | GAAEPHX1CA1CA2DRD2 | |
| SCHEMBL359203 | 0.73 | CTSK (0.59) | GAAEPHX1CA1CA2DRD2 | |
| SCHEMBL31487056 | 0.73 | GAA (0.55) | GAAEPHX1CA1CA2DRD2 | |
| SCHEMBL5351400 | 0.72 | KMT2A (0.37) | GAAEPHX1DRD2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166590-B2 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | GAA 3754/4885EPHX1 1447/4885CA1 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.