SCHEMBL5352290

SCHEMBL5352290

CCCCCCC1=C2c3c(-c4ccc(C(C)(C)C)cc4)cccc3C1[Zr](Cc1ccccc1)(Cc1ccccc1)C1C(CCCCCC)=C(c3c(-c4ccc(C(C)(C)C)cc4)cccc31)C2C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.31
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6519528 0.75 EGFR (0.31)
SCHEMBL5354285 0.71
SCHEMBL5359571 0.68 BRD4 (0.34)
SCHEMBL7185209 0.67 GHSR (0.32)
SCHEMBL5353636 0.67 KMT2A (0.31)
Hydrochloric Acid SCHEMBL3691143 0.67
SCHEMBL7181813 0.66 BRD4 (0.31)
SCHEMBL5914864 0.64
SCHEMBL7186241 0.63
SCHEMBL29086554 0.62 GPR3 (0.46) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed
EP-1054911-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP claimed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 US claimed
US-6350830-B1 SUPPORTED POLYMERIZATION CATALYSTS TAGOR GMBH (DE) 2002-02-26 US claimed
US-7202190-B1 Supported catalyst system for the polymerization of olefins TARGOR GMBH (DE) 2007-04-10 US disclosed
US-7101940-B2 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-09-05 US disclosed
US-7034173-B2 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-04-25 US disclosed
US-6953829-B2 Catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2005-10-11 US disclosed
US-6861384-B2 Process for preparation of a salt-like chemical compound and its use in catalyst systems for preparing polyolefins BASELL POLYOLEFINE GMBH (DE) 2005-03-01 US disclosed
US-20040072975-A1 Salt-like chemical compound, its preparation and its use in catalyst systems for preparing polyolefins BASELL POLYPROPYLEN GMBH (DE) 2004-04-15 US disclosed
US-20040048992-A1 Process for preparation of salt-like chemical compound, and its use in catalyst systems for preparing polyolefins EQUISTAR CHEMICALS, LP 2004-03-11 US disclosed
US-20030144434-A1 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-07-31 US disclosed
US-20030109652-A1 Catalyst system BOHNEN HANS (DE) 2003-06-12 US disclosed
US-6576723-B1 Coordination catalyst comprising metallocene, organoboroaluminum, Lewis base and organometallic compound BASELL POLYOLEFINE GMBH (DE) 2003-06-10 US disclosed
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins SCHOTTEK JORG (DE) 2003-04-10 US disclosed
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-01-16 US disclosed
US-20030008984-A1 Novel catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2003-01-09 US disclosed
US-6500908-B1 ORGANOBORON-ALUMINUM COMPOUND, METALLOCENE, COCATALYTICALLY ACTIVE COMPOUND; BIS(DIMETHYLALUMINOXY)PENTAFLUOROPHENYLBORANE; OLEFIN POLYMERIZATION CATALYST BASELL POLYOLEFINE GMBH (DE) 2002-12-31 US disclosed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 US disclosed
US-6350830-B1 SUPPORTED POLYMERIZATION CATALYSTS TAGOR GMBH (DE) 2002-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144434-A1 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins CBR1, COX6C, CBR3 HSD11B1 410/4885TLR8 3657/4885
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins CLIC1, HACL2, ADH1C HSD11B1 590/4885TLR8 4162/4885
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins SCO2, CNOT1, CYC1 HSD11B1 225/4885TLR8 4783/4885
US-20040048992-A1 Process for preparation of salt-like chemical compound, and its use in catalyst systems for preparing polyolefins CLIC1, HACL2, RFC1 HSD11B1 203/4885TLR8 4340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.