Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611119 | 1.00 | KDM4E (0.33) | KDM4EHTTATMALDH1A1LMNA | |
| SCHEMBL4612169 | 0.98 | LMNA (0.32) | KDM4EHTTATMLMNATSHR | |
| SCHEMBL7294281 | 0.77 | KDM4E (0.33) | KDM4EHTTATM | |
| SCHEMBL7287901 | 0.77 | KDM4E (0.33) | KDM4EHTTATM | |
| SCHEMBL12440638 | 0.75 | KDM4E (0.36) | KDM4EHTTATMALDH1A1 | |
| SCHEMBL10597112 | 0.75 | KDM4E (0.33) | KDM4EHTTATM | |
| SCHEMBL13292098 | 0.72 | TSHR (0.36) | ALDH1A1LMNATSHRHSD11B1 | |
| SCHEMBL17954008 | 0.70 | OPRK1 (0.36) | KDM4EHTTATMALDH1A1 | |
| SCHEMBL13292092 | 0.69 | HSD11B1 (0.35) | LMNATSHRHSD11B1 | |
| SCHEMBL5665984 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183423-B1 | Process for the preparation of organic compounds with imide catalysts | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1055654-A1 | PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS | Daicel Chemical Industries, Ltd. (JP) | 2000-11-29 | — | — | EP | disclosed |