Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ATIC | P31939 | 1/20 | 0.50 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.50 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353001 | 1.00 | MAPT (0.54) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL29189086 | 0.88 | PTGS2 (0.68) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6123725 | 0.87 | ATIC (0.58) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL9009336 | 0.85 | RAB9A (0.54) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL9009308 | 0.85 | RAB9A (0.54) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL9009285 | 0.85 | RAB9A (0.54) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL5720474 | 0.84 | MAPT (0.56) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL5720475 | 0.84 | MAPT (0.56) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL11646096 | 0.83 | ALDH1A1 (0.66) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL11646091 | 0.83 | ALDH1A1 (0.66) | MAPTCYP3A4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197699-A1 | Novel substituted-polyaryl chromophoric compounds | TRANSPHOTONICS, LLC (US) | 2007-08-23 | — | — | US | disclosed |
| US-7205347-B2 | Substituted-polyaryl chromophoric compounds | TRANS PHOTONICS, LLC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20040013375-A1 | Novel substituted-polyaryl chromophoric compounds | TRANS PHOTONICS, L.L.C. | 2004-01-22 | — | — | US | disclosed |
| WO-2002033005-A2 | NOVEL SUBSTITUTED-POLYARYL CHROMOPHORIC COMPOUNDS | TRANS PHOTONICS, L.L.C. (US) | 2002-04-25 | — | — | WO | disclosed |