O-Xylene

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	O-Xylene SCHEMBL9375721	1.00	TSHR (0.50)	TSHRACHECA2MEN1LMNA
	O-Xylene SCHEMBL828121	0.92	TSHR (0.59)	TSHRACHECA2MEN1KMT2A
	Orthocresol SCHEMBL27258627	0.85	TSHR (0.40)	TSHRACHECA2MEN1LMNA
	SCHEMBL27516004	0.83	TAAR1 (0.48)	TSHRCA2ALDH1A1KDM4E
	SCHEMBL21169162	0.83	ALDH1A1 (0.50)	TSHRLMNAKMT2AL3MBTL1ALDH1A1
	Toluene SCHEMBL11563168	0.83	TSHR (0.52)	TSHRACHECA2MEN1LMNA
	Toluene SCHEMBL8205760	0.83	TSHR (0.52)	TSHRACHECA2MEN1LMNA
	SCHEMBL17668299	0.81	ALDH1A1 (0.57)	TSHRMEN1LMNAKMT2AL3MBTL1
	Biphenyl SCHEMBL28018683	0.80	CA2 (0.45)	TSHRCA2MEN1LMNAKMT2A
	O-Xylene SCHEMBL16163023	0.78	TSHR (0.48)	TSHRACHECA2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.