SCHEMBL5353472

SCHEMBL5353472

CCC(N)NC(=O)N(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA4 P43681 1/20 0.35
ACACB O00763 3/20 0.33
USP2 O75604 1/20 0.33
TSHR P16473 1/20 0.33
CAPN1 P07384 1/20 0.33
GAA P10253 1/20 0.31
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP8 P22894 1/20 0.30
CA9 Q16790 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513443 0.74 MMP1 (0.48) ALDH1A1CHRNB2CHRNB4CHRNA4ACACB
SCHEMBL5872362 0.73
SCHEMBL6174733 0.73
SCHEMBL7520516 0.73
SCHEMBL10850954 0.73 ALDH1A1 (0.43) ALDH1A1CHRNB2CHRNB4CHRNA4ACACB
SCHEMBL27738884 0.72 USP2 (0.34) USP2TSHRMMP1MMP2DPP4
Hydrochloric Acid SCHEMBL29001088 0.71
SCHEMBL5898416 0.71
Trimethylammonium SCHEMBL27544246 0.71 TGFBR1 (0.43) LAP3
SCHEMBL27717623 0.70 USP2 (0.32) USP2TSHRDPP8DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7192990-B2 Tertiary amino alkyl amide polyurethane catalysts derived from long chain alkyl and fatty carboxylic acids AIR PRODUCTS AND CHEMICALS, INC. (US) 2007-03-20 US disclosed
US-7189765-B2 Improving the physical properties of polyurethane foams using tertiary amino alkyl amide catalysts AIR PRODUCTS AND CHEMICALS, INC. (US) 2007-03-13 US disclosed
US-6762211-B1 FORMING POROUS, OPEN, DIMENSIONALLY STABLE FOAM; IMPARTING COMPRESSABILITY AND SHRINKAGE RESISTANCE AIR PRODUCTS AND CHEMICALS, INC. 2004-07-13 US disclosed
US-20040132851-A1 Tertiary amino alkyl amide polyurethane catalysts derived from long chain alkyl and fatty carboxylic acids AIR PRODUCTS AND CHEMICALS, INC. 2004-07-08 US disclosed
US-20040132849-A1 Physical properties of polyurethane foams using tertiary amino alkyl amide catalysts AIR PRODUCTS AND CHEMICALS, INC. 2004-07-08 US disclosed