Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359650 | 0.89 | MAPT (0.41) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL5357188 | 0.80 | MAPT (0.42) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL4285291 | 0.78 | TP53 (0.44) | MAPTALDH1A1KMT2AKDM4ETSHR | |
| SCHEMBL3147317 | 0.75 | GABRP (0.40) | MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL3846829 | 0.75 | GAA (0.44) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL28916239 | 0.75 | MAPT (0.43) | MAPTALDH1A1NR4A2KDM4ETSHR | |
| SCHEMBL28916204 | 0.74 | KDM4E (0.42) | MAPTALDH1A1KDM4ETSHRKCNN4 | |
| SCHEMBL31499306 | 0.74 | GAA (0.42) | MAPTKMT2ANR4A2KDM4EGLA | |
| SCHEMBL3893167 | 0.74 | SLC6A3 (0.52) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3846579 | 0.73 | SLC6A3 (0.52) | MAPTALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |