Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 11/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | EPM2A | O95278 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929889 | 0.85 | DHODH (0.53) | DHODHMEN1NPC1CASP3RAB9A | |
| SCHEMBL5355961 | 0.83 | DHODH (0.53) | DHODHMEN1KMT2AADORA2BKDM4E | |
| SCHEMBL5353049 | 0.83 | PTGS2 (0.42) | DHODHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL5359345 | 0.75 | DHODH (0.49) | DHODHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL5354125 | 0.72 | MEN1 (0.50) | DHODHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL14485379 | 0.68 | CNR1 (0.51) | KMOEPM2APTPN6HTR1BMEN1 | |
| SCHEMBL789198 | 0.67 | PLA2G7 (0.48) | NPC1RAB9ANAMPTMAPT | |
| SCHEMBL4522881 | 0.66 | MEN1 (0.70) | MEN1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL4914862 | 0.64 | MAPT (0.70) | DHODHMEN1NPC1CASP3RAB9A | |
| SCHEMBL4212898 | 0.64 | FABP3 (0.55) | KMOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |