Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923649 | 0.82 | SMN1; SMN2 (0.59) | DHODHKMT2AKDM4EMAPTRAB9A | |
| SCHEMBL5353754 | 0.75 | DHODH (0.40) | DHODHPTGDR2KMT2AKDM4EMAPT | |
| SCHEMBL4395519 | 0.75 | NPC1 (0.63) | DHODHKMT2AKDM4EMAPTRAB9A | |
| SCHEMBL18171975 | 0.74 | RAB9A (0.68) | PTGDR2KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL4914862 | 0.73 | MAPT (0.70) | DHODHKMT2AKDM4EMAPTRAB9A | |
| SCHEMBL2877955 | 0.73 | DHODH (0.55) | DHODHPTGDR2KDM1AKMT2AKDM4E | |
| SCHEMBL4395567 | 0.73 | ADORA2B (0.71) | DHODHPTGDR2KMT2AKDM4EMAPT | |
| SCHEMBL20142073 | 0.73 | CCNA2 (0.68) | CDK5CDK5R1KMT2AMAPTRAB9A | |
| SCHEMBL13633763 | 0.72 | CDK5 (0.65) | CDK5CDK5R1KMT2AMAPTRAB9A | |
| SCHEMBL4398263 | 0.71 | CDK5 (0.72) | CDK5CDK5R1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |