Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27924011 | 0.89 | DYRK1A (0.52) | PLA2G7DYRK1ACDK9CA12CA2 | |
| SCHEMBL8906815 | 0.72 | PLA2G7 (0.59) | PLA2G7SYKCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL20529581 | 0.70 | PLA2G7 (0.70) | PLA2G7CYP1A2MAPTNPC1RAB9A | |
| SCHEMBL28151503 | 0.70 | MAPT (0.64) | PLA2G7CYP1A1CYP1A2CYP1B1MAPT | |
| SCHEMBL13153074 | 0.70 | CYP2A6 (0.46) | PRKD1DYRK1ACDK9NAMPT | |
| SCHEMBL23370795 | 0.68 | RAB9A (0.42) | MAPTNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL27630368 | 0.68 | PLA2G7 (0.55) | PLA2G7CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1602410 | 0.68 | HTR1B (0.44) | DYRK1ACDK9 | |
| SCHEMBL3053636 | 0.67 | SYK (0.54) | PLA2G7SYKCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL2981886 | 0.67 | ALDH1A1 (0.61) | PLA2G7SYKCYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037349-A2 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |