Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL5350521 | 0.91 | L3MBTL1 (0.52) | L3MBTL1GAACA1CA2RAB9A | |
| Nitric Acid SCHEMBL5350529 | 0.91 | L3MBTL1 (0.52) | L3MBTL1GAACA1CA2RAB9A | |
| SCHEMBL1185244 | 0.86 | KMT2A (0.58) | L3MBTL1CA1CA2RAB9ALMNA | |
| SCHEMBL11015498 | 0.86 | L3MBTL1 (0.64) | L3MBTL1GAACA1CA2RAB9A | |
| Hydrochloric Acid SCHEMBL29568124 | 0.85 | KMT2A (0.57) | L3MBTL1CA1CA2RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL3839558 | 0.85 | KMT2A (0.57) | L3MBTL1CA1CA2RAB9ALMNA | |
| SCHEMBL895690 | 0.84 | MEN1 (0.63) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6930688 | 0.83 | KMT2A (0.62) | RAB9ATDP1NPSR1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL2546537 | 0.83 | MEN1 (0.61) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12096453 | 0.82 | L3MBTL1 (0.68) | L3MBTL1GAACA1CA2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160897-B2 | Therapeutic compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |
| EP-1341788-B1 | PYRAZOLOPYRIDINES | GLAXO GROUP LTD (GB) | 2005-08-10 | — | — | EP | disclosed |
| US-20050171133-A1 | Therapeutic compounds | CHAMBERLAIN STANLEY D (US) | 2005-08-04 | — | — | US | disclosed |
| US-6919352-B2 | Pyrazolopyridinyl pyridine and pyrimidine therapeutic compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040072853-A1 | Therapeutic compounds | CHAMBERLAIN STANLEY D (US) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072853-A1 | Therapeutic compounds | PCSK9, ABCB1, FURIN | L3MBTL1 4861/4885GAA 63/4885CA1 2208/4885 |
| US-20050171133-A1 | Therapeutic compounds | PCSK9, FURIN, CYP11B2 | L3MBTL1 4860/4885GAA 62/4885CA1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.