Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.59 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.59 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216488 | 0.88 | KCNK3 (0.62) | L3MBTL1GAATDP1RAB9ABLM | |
| SCHEMBL7745302 | 0.87 | KCNK3 (0.79) | L3MBTL1GAATDP1RAB9ABLM | |
| SCHEMBL11031257 | 0.85 | ALDH1A1 (0.71) | L3MBTL1GAAATMTDP1RAB9A | |
| SCHEMBL11015498 | 0.85 | L3MBTL1 (0.64) | L3MBTL1GAAATMTDP1RAB9A | |
| SCHEMBL23932088 | 0.84 | KMT2A (0.66) | L3MBTL1RAB9ACA2KCNK3KCNK9 | |
| SCHEMBL4102809 | 0.82 | KMT2A (0.73) | TDP1RAB9ANPSR1ALDH1A1LMNA | |
| SCHEMBL14982062 | 0.82 | MAPK13 (0.74) | L3MBTL1GAAATMTDP1RAB9A | |
| SCHEMBL5354517 | 0.82 | L3MBTL1 (0.60) | L3MBTL1GAAATMTDP1RAB9A | |
| SCHEMBL24166608 | 0.82 | L3MBTL1 (0.65) | L3MBTL1GAAATMTDP1RAB9A | |
| SCHEMBL27497992 | 0.82 | RAB9A (0.74) | L3MBTL1RAB9APDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496581-A1 | CONDENSED AZEPINE DERIVATIVES AS BROMODOMAIN INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-12 | — | — | EP | disclosed |