Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | PTH1R | Q03431 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NGF | P01138 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351487 | 0.85 | PTH1R (0.36) | ALDH1A1PTH1RSMN1; SMN2CHRM1PDE4A | |
| SCHEMBL5355360 | 0.84 | BRD4 (0.36) | ALDH1A1PTH1RRECQLSMN1; SMN2CREBBP | |
| SCHEMBL5355357 | 0.84 | BRD4 (0.36) | ALDH1A1PTH1RRECQLSMN1; SMN2CREBBP | |
| SCHEMBL5321928 | 0.83 | ALDH1A1 (0.35) | ALDH1A1PTH1RBLMSMN1; SMN2CREBBP | |
| SCHEMBL5358455 | 0.83 | BCHE (0.37) | ALDH1A1PTH1RCREBBPCHRM1NR1I2 | |
| SCHEMBL5362739 | 0.81 | PTH1R (0.35) | PTH1RMAPTSMN1; SMN2CREBBPCHRM1 | |
| SCHEMBL5323349 | 0.80 | ALDH1A1 (0.34) | ALDH1A1PTH1RMEN1MAPTRECQL | |
| SCHEMBL5329713 | 0.78 | PTH1R (0.45) | ALDH1A1PTH1RCHRM1NR1I2KDM4B | |
| SCHEMBL5326023 | 0.78 | PTH1R (0.37) | PTH1R | |
| SCHEMBL5355040 | 0.74 | PTH1R (0.39) | ALDH1A1PTH1RPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |