Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355357 | 1.00 | BRD4 (0.36) | BRD4CREBBPRAB9ASMN1; SMN2PKM | |
| SCHEMBL5355386 | 0.84 | ALDH1A1 (0.36) | CREBBPSMN1; SMN2RECQLPTH1RALDH1A1 | |
| SCHEMBL5326023 | 0.78 | PTH1R (0.37) | BRD4PTH1RCCKBRKDM4E | |
| SCHEMBL5321928 | 0.77 | ALDH1A1 (0.35) | CREBBPRAB9ASMN1; SMN2PTH1RCCKBR | |
| SCHEMBL5358455 | 0.77 | BCHE (0.37) | CREBBPPTH1RCCKBRALDH1A1 | |
| SCHEMBL5355040 | 0.77 | PTH1R (0.39) | BRD4PTH1RCCKBRALDH1A1 | |
| SCHEMBL5349636 | 0.76 | PTH1R (0.47) | PTH1R | |
| SCHEMBL5349639 | 0.76 | PTH1R (0.47) | PTH1R | |
| SCHEMBL5329713 | 0.75 | PTH1R (0.45) | RAB9APTH1RCCKBRKDM4ENPC1 | |
| SCHEMBL5362739 | 0.75 | PTH1R (0.35) | CREBBPSMN1; SMN2PTH1RCCKBRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |