SCHEMBL5355206

SCHEMBL5355206

O=C(CCCCCCCC(=O)N(CCO)CCO)N(CCO)CCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
GPR84 Q9NQS5 1/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.37
POLB P06746 1/20 0.36
KDM4A O75164 7/20 0.35
KDM4C Q9H3R0 7/20 0.35
KDM5A P29375 1/20 0.35
KDM7A Q6ZMT4 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21217233 1.00 LMNA (0.44) LMNAGPR84FFAR1FFAR4ALDH1A1
SCHEMBL4648086 1.00 LMNA (0.44) LMNAGPR84FFAR1FFAR4ALDH1A1
SCHEMBL1202392 1.00 LMNA (0.44) LMNAGPR84FFAR1FFAR4ALDH1A1
SCHEMBL25734860 1.00 LMNA (0.44) LMNAGPR84FFAR1FFAR4ALDH1A1
SCHEMBL132324 0.97 LMNA (0.46) LMNAGPR84FFAR1FFAR4ALDH1A1
SCHEMBL8454374 0.95 GPR84 (0.48) LMNAGPR84FFAR1FFAR4ALDH1A1
SCHEMBL21802606 0.92 GPR84 (0.44) LMNAGPR84FFAR1FFAR4ALDH1A1
SCHEMBL29407499 0.92 LMNA (0.52) LMNAALDH1A1HPGDPOLBCA12
SCHEMBL17636573 0.91 GPR84 (0.56) LMNAGPR84FFAR1FFAR4ALDH1A1
SCHEMBL2149157 0.91 LMNA (0.38) LMNAGPR84FFAR1FFAR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112442408-B Corrosion inhibitor composition and preparation method thereof 德旭新材料(佛冈)有限公司 2022-05-17 CN claimed
CN-112501618-A Antirust agent and preparation method and application thereof 德旭新材料(佛冈)有限公司 2021-03-16 CN claimed
CN-112442408-A Corrosion inhibitor composition and preparation method thereof 德旭新材料(佛冈)有限公司 2021-03-05 CN claimed
EP-0028469-B1 AQUEOUS THERMOSETTING COATING COMPOSITIONS CONTAINING A WATER-SOLUBLE HYDROXY-AMIDO COMPOUND IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-02 EP claimed
EP-0028469-A1 Aqueous thermosetting coating compositions containing a water-soluble hydroxy-amido compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-05-13 EP claimed
EP-4233853-A1 ADELMIDROL IN ASSOCIATION WITH HYALURONIC ACID FOR USE IN THE TREATMENT OF ARTICULAR CHONDROPATHIES EPITECH GROUP S.p.A. (IT) 2023-08-30 EP disclosed
EP-3827819-B1 ADELMIDROL FOR USE IN THE TREATMENT OF DISEASES CHARACTERIZED BY AN ABNORMAL FIBROSIS OF THE CONNECTIVE TISSUE OF THE LUNG EPITECH GROUP S P A (IT) 2023-05-17 EP disclosed
CN-112442408-B Corrosion inhibitor composition and preparation method thereof 德旭新材料(佛冈)有限公司 2022-05-17 CN disclosed
CN-112442408-B Corrosion inhibitor composition and preparation method thereof 德旭新材料(佛冈)有限公司 2022-05-17 CN disclosed
EP-3162365-B1 ADELMIDROL FOR USE IN THE TREATMENT OF DISEASES SENSITIVE TO THE SPECIFIC AGONISM OF THE PPAR-GAMMA RECEPTOR EPITECH GROUP S P A (IT) 2022-05-04 EP disclosed
US-20210169828-A1 Adelmidrol For Use In Diseases Characterized By Insufficient Agonism Of PPAR-GAMMA Receptor EPITECH GROUP S.P.A. (IT) 2021-06-10 US disclosed
EP-3827819-A1 ADELMIDROL FOR USE IN THE TREATMENT OF DISEASES CHARACTERIZED BY AN ABNORMAL FIBROSIS OF THE CONNECTIVE TISSUE OF THE LUNG EPITECH GROUP S.p.A. (IT) 2021-06-02 EP disclosed
US-8178703-B2 Methods for production of polyols from oils and their use in the production of polyesters and polyurethanes BATTELLE MEMORIAL INSTITUTE (US) 2012-05-15 US disclosed
US-7244767-B2 N-acylvanillinamide derivatives capable of activating peripheral cannabinoid receptors INNOVET ITALIA S.R.L. (IT) 2007-07-17 US disclosed
US-20050065216-A1 Therapy for multiple sclerosis, psoriasis, urticaria; antiarthritic agents; incotinence; antitumor, anticancer agents INNOVET ITALIA S.R.L. (IT) 2005-03-24 US disclosed
EP-1115392-B1 USE OF N-ACYLVANILLINAMIDE DERIVATIVES AS AGONISTS OF PERIPHERAL CANNABINOID CB1 RECEPTORS INNOVET ITALIA SRL (IT) 2002-12-11 EP disclosed
EP-1115392-A2 USE OF N-ACYLVANILLINAMIDE DERIVATIVES AS AGONISTS OF PERIPHERAL CANNABINOID CB1 RECEPTORS Innovet Italia S.r.l. (IT) 2001-07-18 EP disclosed
WO-2000016756-A2 USE OF N-ACYLVANILLINAMIDE DERIVATIVES AS AGONISTS OF PERIPHERAL CANNABINOID CB1 RECEPTORS INNOVET ITALIA S.R.L. (IT) 2000-03-30 WO disclosed
EP-0028469-B1 AQUEOUS THERMOSETTING COATING COMPOSITIONS CONTAINING A WATER-SOLUBLE HYDROXY-AMIDO COMPOUND IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-02 EP disclosed
EP-0028469-A1 Aqueous thermosetting coating compositions containing a water-soluble hydroxy-amido compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065216-A1 Therapy for multiple sclerosis, psoriasis, urticaria; antiarthritic agents; incotinence; antitumor, anticancer agents CNR1, CNR2, GPR18 LMNA 3641/4885GPR84 54/4885FFAR1 25/4885
US-20210169828-A1 Adelmidrol For Use In Diseases Characterized By Insufficient Agonism Of PPAR-GAMMA Receptor PPARD, PPARG, GPR139 LMNA 2761/4885GPR84 23/4885FFAR1 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.