SCHEMBL234271

SCHEMBL234271

O=C(NCCCCCCO)OCc1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.70
TGM2 P21980 1/20 0.70
LMNA P02545 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
KEAP1 Q14145 3/20 0.63
NFE2L2 Q16236 3/20 0.63
FOLH1 Q04609 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.53
DPP8 Q6V1X1 1/20 0.53
DPP7 Q9UHL4 1/20 0.53
MAPT P10636 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
SLC1A3 P43003 1/20 0.51
SLC1A1 P43005 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31400174 1.00 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL11441576 1.00 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL16692078 1.00 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL7037381 1.00 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL17634037 1.00 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL887187 1.00 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL667447 0.98 HTT (0.72) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL16283432 0.94 HTT (0.67) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL535583 0.94 HTT (0.74) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL9874334 0.94 HTT (0.79) HTTTGM2LMNASMN1; SMN2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911795-B1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2025-10-01 EP claimed
CN-113646479-B Method for strengthening non-keratin fibers and use thereof 埃斯普投资有限公司 2023-06-13 CN claimed
US-9150602-B2 Precursor used for labeling hepatorcyte receptor and containing trisaccharide and diamide demercaptide ligand, method for preparing the same, radiotracer and pharmaceutical composition of the same ATOMIC ENERGY COUNCIL, INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) 2015-10-06 US claimed
US-20140031533-A1 PRECURSOR USED FOR LABELING HEPATORCYTE RECEPTOR AND CONTAINING TRISACCHARIDE AND DIAMIDE DEMERCAPTIDE LIGAND, METHOD FOR PREPARING THE SAME, RADIOTRACER AND PHARMACEUTICAL COMPOSITION OF THE SAME ATOMIC ENERGY COUNCIL, INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) 2014-01-30 US claimed
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2026-01-22 US disclosed
EP-4634197-A1 COMPOSITIONS AND METHODS FOR CHEMOPROTEOMICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-10-22 EP disclosed
EP-4615487-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES Merck Sharp & Dohme LLC (US) 2025-09-17 EP disclosed
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
EP-4573102-A2 COMPOSITIONS AND METHODS FOR CHEMOPROTEOMIC REAGENT SYNTHESIS AND APPLICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-06-25 EP disclosed
US-20240424109-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2024-12-26 US disclosed
CN-114929729-B Nucleic acid complex and pharmaceutical composition containing the same 卫材R&D管理有限公司 2024-12-03 CN disclosed
EP-4436610-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES Merck Sharp & Dohme LLC (US) 2024-10-02 EP disclosed
EP-0501250-A1 Fucose-marked batracylin derivatives BAYER AG (DE) 1992-09-02 EP disclosed
EP-0420806-A1 Phosphonic acids, process for preparation and use as an active pharmaceutical composition CIBA-GEIGY AG (CH) 1991-04-03 EP disclosed
US-4668769-A Oxa- and azahomocyclostatine polypeptides PFIZER INC. 1987-05-26 US disclosed
EP-0211580-A2 Renin inhibiting polypeptides and intermediates therefor PFIZER INC. (US) 1987-02-25 EP disclosed
US-4599198-A Intermediates in polypeptide synthesis PFIZER INC. (US) 1986-07-08 US disclosed
US-4550163-A Ligand analog-irreversible enzyme inhibitor conjugates ABBOTT LABORATORIES (US) 1985-10-29 US disclosed
US-4273866-A IMMUNOASSAY FOR QUANTITATIVE ANALYSIS OF ACETYLCHOLINESTERASE ABBOTT LABORATORIES (US) 1981-06-16 US disclosed
US-4228274-A 1-Substituted glycopyranosides MERCK & CO., INC. (US) 1980-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES INSR, GPR119, GLP1R HTT 1719/4885TGM2 1041/4885LMNA 4564/4885
US-20140031533-A1 PRECURSOR USED FOR LABELING HEPATORCYTE RECEPTOR AND CONTAINING TRISACCHARIDE AND DIAMIDE DEMERCAPTIDE LIGAND, METHOD FOR PREPARING THE SAME, RADIOTRACER AND PHARMACEUTICAL COMPOSITION OF THE SAME ASGR1, M6PR, DDOST HTT 3450/4885TGM2 776/4885LMNA 4135/4885
US-20240424109-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES GPR119, INSR, IAPP HTT 982/4885TGM2 659/4885LMNA 4837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.