SCHEMBL667447

SCHEMBL667447

O=C(NCCCCO)OCc1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.72
TGM2 P21980 1/20 0.68
LMNA P02545 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
KEAP1 Q14145 3/20 0.64
NFE2L2 Q16236 3/20 0.64
FOLH1 Q04609 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.55
DPP8 Q6V1X1 1/20 0.54
DPP7 Q9UHL4 1/20 0.54
MAPT P10636 1/20 0.53
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
SLC1A3 P43003 1/20 0.52
SLC1A1 P43005 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17634037 0.98 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL16692078 0.98 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL234271 0.98 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL7037381 0.98 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL887187 0.98 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL31400174 0.98 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL11441576 0.98 HTT (0.70) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL16283432 0.95 HTT (0.67) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL535583 0.95 HTT (0.74) HTTTGM2LMNASMN1; SMN2KEAP1
SCHEMBL2453444 0.94 HTT (0.65) HTTTGM2LMNASMN1; SMN2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911795-B1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2025-10-01 EP claimed
CN-113646479-B Method for strengthening non-keratin fibers and use thereof 埃斯普投资有限公司 2023-06-13 CN claimed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 US disclosed
WO-2025235840-A1 ECHINOCANDIN-LIKE AND BORON-CONTAINING ECHINOCANDIN COMPOUNDS AND THEIR USE AS AGROCHEMICAL FUNGICIDES 5METIS, INC. (US) 2025-11-13 WO disclosed
EP-3911795-B1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2025-10-01 EP disclosed
EP-3917926-B1 IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE THEREOF CANWELL BIOTECH LTD (HK) 2025-10-01 EP disclosed
US-12383624-B2 Cargo delivery system and composition comprising the same SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-12 US disclosed
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
US-12201688-B2 Lipidated immune response modifier compound compositions, formulations, and methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-01-21 US disclosed
US-12122772-B2 Imidazoquinoline amine derivatives, pharmaceutical compositions and therapeutic methods thereof CANWELL BIOTECH LIMITED (CN) 2024-10-22 US disclosed
US-20240252617-A1 CORONAVIRUS SPIKE PROTEIN DESIGNS, COMPOSITIONS AND METHODS FOR THEIR USE DUKE UNIVERSITY 2024-08-01 US disclosed
US-5652213-A CYCLIC HEXAPEPTIDE FUNGICIDES, PARASITICIDES ELI LILLY AND COMPANY (US) 1997-07-29 US disclosed
WO-1996037510-A1 CYCLIC PEPTIDE ANTIFUNGAL AGENTS ELI LILLY AND COMPANY (US) 1996-11-28 WO disclosed
EP-0744405-A2 Cyclic peptide antifungal agents ELI LILLY AND COMPANY (US) 1996-11-27 EP disclosed
US-4742067-A Acylalkylaminocarbonyl substituted amino and imino acid compounds E. R. SQUIBB & SONS, INC. (US) 1988-05-03 US disclosed
US-4621092-A HYPOTENSIVE, ANALGESIC E. R. SQUIBB & SONS, INC. (US) 1986-11-04 US disclosed
US-4604402-A HYPOTENSIVE AGNETS E. R. SQUIBB & SONS, INC. (US) 1986-08-05 US disclosed
EP-0159156-A1 Hydroxy substituted ureido amino and imino acids E.R. Squibb & Sons, Inc. (US) 1985-10-23 EP disclosed
EP-0103496-A1 Acylalkylaminocarbonyl substituted amino and imino acid compounds E.R. Squibb & Sons, Inc. (US) 1984-03-21 EP disclosed
US-4180565-A ANTIBACTERIAL AGENTS, ANTIBIOTICS SCHERING CORPORATION (US) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 HTT 1159/4885TGM2 494/4885LMNA 2788/4885
US-12383624-B2 Cargo delivery system and composition comprising the same ATG7, SQSTM1, BECN1 HTT 112/4885TGM2 2410/4885LMNA 1430/4885
US-12122772-B2 Imidazoquinoline amine derivatives, pharmaceutical compositions and therapeutic methods thereof TLR8, TLR7, TLR1 HTT 4718/4885TGM2 3564/4885LMNA 3434/4885
US-12201688-B2 Lipidated immune response modifier compound compositions, formulations, and methods IRF3, IFNG, STING1 HTT 4243/4885TGM2 3611/4885LMNA 3804/4885
US-20240252617-A1 CORONAVIRUS SPIKE PROTEIN DESIGNS, COMPOSITIONS AND METHODS FOR THEIR USE SARS1, CD14, ACE2 HTT 1998/4885TGM2 825/4885LMNA 4066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.