Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623371 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL21239496 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL6108042 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL28878544 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL29291809 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL7206146 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL7944901 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL8580399 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL8643594 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL4550673 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119101668-B | Mutant enzyme, fermentation production method thereof and application of mutant enzyme in preparation of buckwheat alkali | 华南师范大学 | 2025-05-09 | — | — | CN | claimed |
| CN-119101668-A | Mutant enzyme, fermentation production method thereof and application of mutant enzyme in preparation of buckwheat alkali | 华南师范大学 | 2024-12-10 | — | — | CN | claimed |
| CN-119101668-B | Mutant enzyme, fermentation production method thereof and application of mutant enzyme in preparation of buckwheat alkali | 华南师范大学 | 2025-05-09 | — | — | CN | disclosed |
| CN-119101668-A | Mutant enzyme, fermentation production method thereof and application of mutant enzyme in preparation of buckwheat alkali | 华南师范大学 | 2024-12-10 | — | — | CN | disclosed |
| US-10174132-B2 | Heparan sulfate synthesis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2016-03-03 | — | — | US | disclosed |
| US-20120142560-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| EP-2414371-A2 | HEPARAN SULFATE SYNTHESIS | The University Of Georgia Research Foundation, Inc (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010117803-A2 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100256098-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2010-10-07 | — | — | US | disclosed |
| EP-2188296-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009029844-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256098-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | WAPL, WDR1, DUSP1 | ALDH1A1 1064/4885TDP1 1049/4885KMT2A 1591/4885 |
| US-10174132-B2 | Heparan sulfate synthesis | HPSE, STT3B, DDOST | ALDH1A1 3615/4885TDP1 4697/4885KMT2A 2909/4885 |
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | HPSE, STT3B, DDOST | ALDH1A1 3615/4885TDP1 4697/4885KMT2A 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.