Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14216867 | 0.77 | MAOB (0.38) | LMNAMEN1CA1CA2CA5A | |
| SCHEMBL14216812 | 0.76 | ALDH1A1 (0.36) | KIF11ALDH1A1MAPTBLMPMP22 | |
| SCHEMBL17625640 | 0.75 | TSHR (0.37) | ALDH1A1TSHR | |
| SCHEMBL24400504 | 0.74 | ESR1 (0.45) | ESR1ESR2SLC6A3 | |
| SCHEMBL31410709 | 0.74 | — | — | |
| SCHEMBL17625650 | 0.72 | CES1 (0.35) | CA2 | |
| SCHEMBL24209554 | 0.72 | LOXL2 (0.41) | CA12CA1CA2CA4CA5A | |
| SCHEMBL19090382 | 0.71 | MAPT (0.44) | HPGDMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL17625661 | 0.71 | PTPRZ1 (0.49) | MMP2 | |
| SCHEMBL15895082 | 0.70 | HDAC6 (0.47) | HPGDCA2PDK2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232914-B2 | Sphingomyelin analogues and a process for preparation thereof | DAISO CO., LTD (JP) | 2007-06-19 | — | — | US | claimed |
| US-20060008518-A1 | Sphingomyelin analogues and a process for preparation thereof | DAISO CO., LTD. (JP) | 2006-01-12 | — | — | US | claimed |
| US-7232914-B2 | Sphingomyelin analogues and a process for preparation thereof | DAISO CO., LTD (JP) | 2007-06-19 | — | — | US | disclosed |
| US-20060008518-A1 | Sphingomyelin analogues and a process for preparation thereof | DAISO CO., LTD. (JP) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060008518-A1 | Sphingomyelin analogues and a process for preparation thereof | SGMS1, SGMS2, SMPD1 | ESR1 3980/4885ESR2 3954/4885KIF11 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.