SCHEMBL5356245

SCHEMBL5356245

CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1N1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 3/20 0.43
▸ LGALS8 O00214 3/20 0.38
▸ FGF1 P05230 1/20 0.38
▸ CA2 P00918 2/20 0.37
▸ CA9 Q16790 2/20 0.37
▸ CA1 P00915 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ PTPN1 P18031 2/20 0.35
▸ G6PD P11413 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5360431 0.84 FGF1 (0.32) OGAFGF1CA2CA9CA1
SCHEMBL25344927 0.82 LMNA (0.37) —
SCHEMBL30180561 0.82 LMNA (0.37) —
SCHEMBL24917500 0.82 LMNA (0.37) —
SCHEMBL22529151 0.80 OGA (0.53) OGALGALS8PTPN1
SCHEMBL22542460 0.80 OGA (0.53) OGALGALS8PTPN1
SCHEMBL21001779 0.80 OGA (0.53) OGALGALS8PTPN1
SCHEMBL2741356 0.80 OGA (0.53) OGALGALS8PTPN1
SCHEMBL25866953 0.79 OGA (0.46) OGALGALS8FGF1CA2CA9
SCHEMBL25871496 0.79 OGA (0.46) OGALGALS8FGF1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7230096-B2 Inhibitors against galectins FORSKARPATENT I SYD AB (SE) 2007-06-12 — — US disclosed
US-20040147730-A1 Inhibitors against galectins FORSKARPATENT I SYD AB (SE) 2004-07-29 — — US disclosed
EP-1353934-A1 NEW INHIBITORS AGAINST GALECTINS Nilsson, Ulf (SE) 2003-10-22 — — EP disclosed
WO-2002057284-A1 NEW INHIBITORS AGAINST GALECTINS NILSSON ULF (SE) 2002-07-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147730-A1 Inhibitors against galectins LGALS1, LGALS3, LGALS2 OGA 200/4885LGALS8 6/4885FGF1 3160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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