Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235262 | 0.94 | APP (0.57) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL7019557 | 0.94 | APP (0.57) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL3021121 | 0.94 | APP (0.57) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL16758740 | 0.94 | APP (0.57) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL15814832 | 0.90 | APP (0.50) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL17963081 | 0.89 | TDP1 (0.57) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL5505 | 0.89 | TDP1 (0.57) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL9784265 | 0.88 | TDP1 (0.64) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL3482694 | 0.88 | TDP1 (0.64) | TDP1TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL8339774 | 0.88 | MAPT (0.52) | RAB9AMAPTL3MBTL1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108931-B | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2024-06-14 | — | — | CN | claimed |
| CN-115232076-A | Phenylamino substituted pyrimidine amino acid derivative and preparation method and application thereof | 南通大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115108931-A | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2022-09-27 | — | — | CN | claimed |
| EP-3735407-B1 | SUBSTITUTED HALO-QUINOLINE DERIVATES FOR USE IN THE TREATMENT OF LYMPHOMAS AND LEUKEMIA | INST NAT SANTE RECH MED (FR) | 2026-04-01 | — | — | EP | disclosed |
| US-12559454-B2 | Benzenesulfonamide derivatives and uses thereof | 2692372 ONTARIO, INC. (CA) | 2026-02-24 | — | — | US | disclosed |
| EP-4638427-A1 | AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | Université Côte d'Azur (FR) | 2025-10-29 | — | — | EP | disclosed |
| CN-114763346-B | Compounds for inducing cartilage formation and application thereof | 华东师范大学 | 2025-06-10 | — | — | CN | disclosed |
| EP-4522618-A1 | TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS | Merck Patent GmbH (DE) | 2025-03-19 | — | — | EP | disclosed |
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| EP-3617213-B1 | THIENO[3,2-D]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES | HANMI PHARMACEUTICAL CO LTD (KR) | 2025-02-19 | — | — | EP | disclosed |
| US-20240327393-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-10-03 | — | — | US | disclosed |
| US-4199318-A | Washfast disazo dyestuffs | TOMS RIVER CHEMICAL CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |
| US-4176229-A | CATIONIC INDOLE DYE USED ON ANIONICALLY MODIFIED FIBERS | BASF AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |
| EP-0004400-A2 | Photographic diffusion transfer process and material for the production of colour images and suitable compounds therefor | AGFA-GEVAERT N.V. (BE) | 1979-10-03 | — | — | EP | disclosed |
| US-4168264-A | PRINTING AND DYEING OF POLYACRYLONITRILE TEXTILES | CIBA-GEIGY CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |
| US-4157443-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-06-05 | — | — | US | disclosed |
| US-4143035-A | DISAZO DYESTUFFS HAVING AN ALKOXY GROUP ON THE FIRST AND/OR SECOND COMPONENT | TOMS RIVER CHEMICAL CORPORATION (US) | 1979-03-06 | — | — | US | disclosed |
| US-4104284-A | Nitroanthraquinones | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-3992421-A | ANTHRAQUINONE DYESTUFFS FOR BLUE DYEINGS OF POLYESTERS | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3989450-A | DYEING AND PRINTING SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327393-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | AIFM2, GPX1, GPX4 | TDP1 4531/4885TSHR 1399/4885MAPK1 2630/4885 |
| US-12559454-B2 | Benzenesulfonamide derivatives and uses thereof | NR2E1, NR2C2, NR3C1 | TDP1 3479/4885TSHR 39/4885MAPK1 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.