SCHEMBL1235262

SCHEMBL1235262

COCCOCCOCCOc1ccc(N)cc1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.57
TDP1 Q9NUW8 4/20 0.53
KDM4E B2RXH2 1/20 0.53
RECQL P46063 1/20 0.53
TSHR P16473 1/20 0.52
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 1/20 0.45
CYP3A4 P08684 1/20 0.45
NFE2L2 Q16236 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7019557 1.00 APP (0.57) APPTDP1KDM4ERECQLTSHR
SCHEMBL3021121 1.00 APP (0.57) APPTDP1KDM4ERECQLTSHR
SCHEMBL16758740 1.00 APP (0.57) APPTDP1KDM4ERECQLTSHR
SCHEMBL5357 0.94 TDP1 (0.59) APPTDP1KDM4ERECQLTSHR
SCHEMBL15814832 0.92 APP (0.50) APPTDP1KDM4ERECQLTSHR
SCHEMBL15071342 0.89 APP (0.67) APPTDP1KDM4ETSHRNPC1
SCHEMBL3611926 0.89 KDM4E (0.61) APPTDP1KDM4ERECQLMAPK1
SCHEMBL12703538 0.89 KDM4E (0.61) APPTDP1KDM4ERECQLMAPK1
SCHEMBL1353069 0.89 APP (0.67) APPTDP1KDM4ETSHRNPC1
SCHEMBL7911522 0.89 APP (0.67) APPTDP1KDM4ETSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543856-A1 BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 Asha Therapeutics LLC (US) 2025-04-30 EP disclosed
WO-2023249965-A1 BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 ASHA THERAPEUTICS LLC (US) 2023-12-28 WO disclosed
EP-3173414-A1 HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS ACEA Biosciences Inc. (US) 2017-05-31 EP disclosed
US-9645153-B2 Labeling reagents and methods of their use Life Technologies Corporation (US) 2017-05-09 US disclosed
US-9645153-B2 Labeling reagents and methods of their use Life Technologies Corporation (US) 2017-05-09 US disclosed
US-9645153-B2 Labeling reagents and methods of their use Life Technologies Corporation (US) 2017-05-09 US disclosed
EP-2188271-B1 HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS ACEA BIOSCIENCES INC (US) 2017-01-11 EP disclosed
US-20160046576-A1 NOVEL PYRROLE DERIVATIVES UNIV LEICESTER (GB) 2016-02-18 US disclosed
US-20150355186-A1 Labeling Reagents and Methods of Their Use INVITROGEN CORPORATION 2015-12-10 US disclosed
US-20150355186-A1 Labeling Reagents and Methods of Their Use INVITROGEN CORPORATION 2015-12-10 US disclosed
US-20090004753-A1 LABELING REAGENTS AND METHODS OF THEIR USE INVITROGEN CORPORATION (US) 2009-01-01 US disclosed
US-20090004753-A1 LABELING REAGENTS AND METHODS OF THEIR USE INVITROGEN CORPORATION (US) 2009-01-01 US disclosed
US-7459137-B2 Process for functionalizing carbon nanotubes under solvent-free conditions WILLIAM MARSH RICE UNIVERSITY (US) 2008-12-02 US disclosed
US-7384815-B2 One step; high functionality; maintains critical properties; polymer composite materials, molecular electronics, sensor devices WILLIAM MARSH RICE UNIVERSITY (US) 2008-06-10 US disclosed
US-7250147-B2 One step; high functionality; maintains critical properties; polymer composite materials, molecular electronics, sensor devices NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2007-07-31 US disclosed
EP-1778700-A1 SYNTHETICALLY EXPEDIENT WATER-DISPERSIBLE IR DYES Silverbrook Research Pty. Ltd (AU) 2007-05-02 EP disclosed
US-20060272545-A1 Inkjet lnks for printing coded data comprising naphthalocyanine dyes SILVERBROOK RESEARCH PTY LTD 2006-12-07 US disclosed
US-7122076-B2 Synthetically expedient water-dispersible IR dyes SILVERBROOK RESEARCH PTY LTD (AU) 2006-10-17 US disclosed
WO-2006015414-A1 SYNTHETICALLY EXPEDIENT WATER-DISPERSIBLE IR DYES SILVERBROOK RESEARCH PTY LTD (AU) 2006-02-16 WO disclosed
US-20060030706-A1 Synthetically expedient water-dispersible IR dyes SILVERBROOK RESEARCH PTY LTD 2006-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150355186-A1 Labeling Reagents and Methods of Their Use GUSB, CES2, MRPL21 APP 4167/4885TDP1 2001/4885KDM4E 3693/4885
US-20160046576-A1 NOVEL PYRROLE DERIVATIVES PYCR1, ARG1, PNISR APP 2881/4885TDP1 971/4885KDM4E 1392/4885
US-20060030706-A1 Synthetically expedient water-dispersible IR dyes SLC39A11, SLC13A3, SLC39A3 APP 4746/4885TDP1 1869/4885KDM4E 4645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.