Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951372 | 0.82 | MAPT (0.56) | SIRT2ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL6201771 | 0.75 | PARP1 (0.39) | ALDH1A1PARP1CA12CA9MAPT | |
| SCHEMBL11751133 | 0.73 | TDP1 (0.46) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL7034341 | 0.73 | PARP1 (0.71) | SIRT2ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL10943186 | 0.72 | TDP1 (0.56) | ALDH1A1TDP1CYP3A4ALOX15CA12 | |
| SCHEMBL5350366 | 0.72 | CA12 (0.55) | SIRT2ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL5359827 | 0.72 | CA12 (0.55) | SIRT2ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL25330088 | 0.71 | SIRT2 (0.41) | SIRT2ALDH1A1CYP3A4PARP1CA12 | |
| SCHEMBL8129404 | 0.69 | MAPT (0.60) | SIRT2ALDH1A1CYP3A4ALOX15PARP1 | |
| SCHEMBL17883976 | 0.68 | CA12 (0.54) | SIRT2ALDH1A1CYP3A4PARP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262284-B2 | Method for producing disazo pigments | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-08-28 | — | — | US | disclosed |
| US-20060167236-A1 | Method for producing disazo pigments | CLARIANT GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1517962-A1 | METHOD FOR PRODUCING DISAZO PIGMENTS | Clariant GmbH (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000947-A1 | METHOD FOR PRODUCING DISAZO PIGMENTS | CLARIANT GMBH (DE) | 2003-12-31 | — | — | WO | disclosed |
| EP-0585873-B1 | Method of preparing disazo pigments | CLARIANT GMBH (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5559216-A | AZO COUPLING | HOECHST AG (DE) | 1996-09-24 | — | — | US | disclosed |
| US-5493011-A | PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS | HOECHST AG (DE) | 1996-02-20 | — | — | US | disclosed |
| EP-0518909-B1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AG (DE) | 1994-05-25 | — | — | EP | disclosed |
| EP-0585873-A1 | Method of preparing disazo pigments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-09 | — | — | EP | disclosed |
| EP-0518909-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. | HOECHST AG (DE) | 1992-12-23 | — | — | EP | disclosed |
| EP-0316649-B1 | WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-22 | — | — | EP | disclosed |
| WO-1991013941-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-19 | — | — | WO | disclosed |
| US-5026831-A | Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-25 | — | — | US | disclosed |
| EP-0316649-A2 | Water insoluble azo colouring agents, their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167236-A1 | Method for producing disazo pigments | TYR, IPO4, CBR3 | SIRT2 1153/4885ALDH1A1 560/4885TDP1 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.